Hyuga Taiju, Nakamura Shigeru, Kawai Shina, Nakai Hideo
Department of Pediatric Urology, Children's Medical Center Tochigi, Jichi Medical University, Tochigi, Japan.
Department of Pediatric Urology, Children's Medical Center Tochigi, Jichi Medical University, Tochigi, Japan.
Urology. 2017 Jul;105:153-156. doi: 10.1016/j.urology.2017.01.005. Epub 2017 Jan 12.
To evaluate the effectiveness of a 3-month enuresis alarm (EA) treatment and repeat EA treatment among pediatric patients with nocturnal enuresis, and to compare patient characteristics among "responders" and "nonresponders" to treatment.
Clinical outcomes were retrospectively evaluated for 137 children (94 boys and 43 girls, mean age, 10.1 years). Effectiveness was evaluated after an initial 3-month treatment, using the International Children's Continence Society criteria. Among children in the no-response group at 3 months, those who continued the EA treatment for ≥4 months were subclassified into group 1, whereas children who repeated the EA treatment at an interval ≥6 months were subclassified into group 2.
Among our 137 cases, 19 achieved complete response and 47 achieved partial response at 3 months, for an overall treatment effectiveness rate of 48%. Among the no-response group, treatment was extended in 17 cases (group 1), with 3 (18%) achieving a successful outcome. Treatment was repeated in 18 cases (group 2). In group 2, 8 (44%) achieved successful outcome at 3-month time point. Daytime urinary incontinence did not modify treatment effectiveness.
EA treatment should be given for a short period of time and should not be continued without a definite purpose or clear response. Suspending and then repeating this treatment after an appropriate interval is effective for patients who do not respond to the initial course of treatment.
评估为期3个月的遗尿警报（EA）治疗及重复EA治疗对小儿夜间遗尿症患者的有效性，并比较治疗“反应者”和“无反应者”的患者特征。
对137名儿童（94名男孩和43名女孩，平均年龄10.1岁）的临床结果进行回顾性评估。在最初3个月的治疗后，使用国际儿童尿控协会的标准评估有效性。在3个月时无反应组的儿童中，继续EA治疗≥4个月的被分类为第1组，而间隔≥6个月重复EA治疗的儿童被分类为第2组。
在我们的137例病例中，19例在3个月时达到完全缓解，47例达到部分缓解，总体治疗有效率为48%。在无反应组中，17例（第1组）延长了治疗时间，其中3例（18%）取得了成功的结果。18例（第2组）重复了治疗。在第2组中，8例（44%）在3个月时间点取得了成功的结果。白天尿失禁不影响治疗效果。
EA治疗应在短时间内进行，不应无明确目的或无明显反应地持续进行。对于对初始疗程无反应的患者，在适当间隔后暂停然后重复此治疗是有效的。
