Rai Mahendra, Paralikar Priti, Jogee Priti, Agarkar Gauravi, Ingle Avinash P, Derita Marcos, Zacchino Susana
Department of Biotechnology, Sant Gadge Baba Amravati University, Amravati, 444602, Maharashtra, India.
Department of Biotechnology, Sant Gadge Baba Amravati University, Amravati, 444602, Maharashtra, India.
Int J Pharm. 2017 Mar 15;519(1-2):67-78. doi: 10.1016/j.ijpharm.2017.01.013. Epub 2017 Jan 9.
The development of resistance to different antimicrobial agents by bacteria, fungi, viruses, parasites, etc. is a great challenge to the medical field for the treatment of infections caused by them, and therefore, there is a pressing need to search for new and novel antimicrobials. The antimicrobial activity of essential oils and biogenic nanoparticles is well known. Recent studies have demonstrated that nanoparticles functionalized with essential oils have significant antimicrobial potential against multidrug- resistant pathogens. The aim of the present review is to discuss various studies on the broad-spectrum antimicrobial activity of essential oils used singly and in combination with nanoparticles. The brief explanation of their mechanism has also been discussed.
细菌、真菌、病毒、寄生虫等对不同抗菌剂产生耐药性的发展,给医学领域治疗由它们引起的感染带来了巨大挑战,因此,迫切需要寻找新的和新颖的抗菌剂。精油和生物源纳米颗粒的抗菌活性是众所周知的。最近的研究表明,用精油功能化的纳米颗粒对多重耐药病原体具有显著的抗菌潜力。本综述的目的是讨论关于单独使用精油以及精油与纳米颗粒联合使用的广谱抗菌活性的各种研究。还讨论了它们作用机制的简要解释。