Draelos Zoe Diana, Karnik Jwala, Naughton Gail
J Drugs Dermatol. 2017 Jan 1;16(1):30-34.
Growth factors are a new category of ingredient found in modern cosmeceutical formulations. One novel method of obtaining cosmeceutical growth factors is the use of a bioreactor to culture neonatal broblasts on dextran microcarrier beads for 8 weeks under low oxygen tension (1-5%) mimicking embryonic conditions and eliminating the need for fetal bovine serum constituents in the final cosmetic material. This research evaluated the ingredient in a moisturizing vehicle on 40 females to determine its efficacy in improving overall facial skin appearance, as well as skin brightness, evenness, firmness, pore size, radiance, fine lines, coarse wrinkles, and blotchiness/ dispigmentation. Statistically significant improvement was seen in 90 days in skin hydration through corneometry, as well in global investigator and subject assessments. J Drugs Dermatol. 2017;16(1):30-34..
生长因子是现代药妆配方中发现的一类新成分。一种获取药妆用生长因子的新方法是使用生物反应器，在模拟胚胎条件的低氧张力（1 - 5%）下，将新生成纤维细胞在葡聚糖微载体珠上培养8周，并在最终的化妆品原料中无需胎牛血清成分。这项研究在40名女性的保湿载体中评估了该成分，以确定其在改善整体面部皮肤外观以及皮肤亮度、均匀度、紧致度、毛孔大小、光泽度、细纹、粗皱纹和斑点/色素沉着方面的功效。通过角质层水合测量法，在90天内皮肤水合作用有统计学意义的改善，在全球研究者和受试者评估中也是如此。《皮肤药物学杂志》。2017年；16(1):30 - 34。
