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戈登链球菌——全髋关节置换术中人工关节感染的罕见病因。

Streptococcus gordonii-a rare cause of prosthetic joint infection in a total hip replacement.

作者信息

Fenelon Christopher, Galbraith John G, Dalton David M, Masterson Eric

机构信息

Department of Orthopaedic Surgery, University Hospital Limerick, Limerick, Ireland

Department of Orthopaedic Surgery, University Hospital Limerick, Limerick, Ireland.

出版信息

J Surg Case Rep. 2017 Jan 16;2017(1):rjw235. doi: 10.1093/jscr/rjw235.

DOI:10.1093/jscr/rjw235
PMID:28096320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5241763/
Abstract

A 69-year-old female with a history of bilateral total hip replacements presented with rigors, fever and sudden onset left groin pain. A pelvic X-ray showed well-fixed implants. Blood results revealed a leucocytosis (white cell count 22.3 × 10 l) and elevated C-reactive protein (211 mg/l). Ultrasound-guided aspiration of her left hip grew Streptococcus gordonii No source infection could be identified apart from a new chronic sinus infection in a left upper incisor. Following a discussion with the patient a 6-week course of intravenous ceftriaxone was started and was successful in normalizing her inflammatory markers. She was placed on long-term suppressive amoxicillin following this. Her suppressive antibiotic therapy was complicated by the development of a clostridium difficile infection and her antibiotics were changed to doxycycline. At 1-year follow-up, she was asymptomatic with no further episodes of groin pain or fever.

摘要

一名69岁有双侧全髋关节置换史的女性出现寒战、发热及突发左侧腹股沟疼痛。骨盆X线显示植入物固定良好。血液检查结果显示白细胞增多(白细胞计数22.3×10⁹/L)及C反应蛋白升高(211mg/L)。超声引导下对其左髋关节进行穿刺抽吸,培养出戈登链球菌。除左上侧切牙新出现的慢性鼻窦感染外,未发现其他感染源。与患者讨论后,开始了为期6周的静脉注射头孢曲松治疗,炎症指标恢复正常。此后她接受了长期的阿莫西林抑制性治疗。她的抑制性抗生素治疗因艰难梭菌感染而变得复杂,抗生素改为强力霉素。随访1年时,她无症状,未再出现腹股沟疼痛或发热发作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d91/5241763/b71045aab64f/rjw235f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d91/5241763/aafbd69c0908/rjw235f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d91/5241763/da106da39ed3/rjw235f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d91/5241763/b71045aab64f/rjw235f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d91/5241763/aafbd69c0908/rjw235f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d91/5241763/da106da39ed3/rjw235f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d91/5241763/b71045aab64f/rjw235f03.jpg

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本文引用的文献

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BMJ Case Rep. 2015 Aug 11;2015:bcr2015210695. doi: 10.1136/bcr-2015-210695.
2
Outcome of patients over 80 years of age on prolonged suppressive antibiotic therapy for at least 6 months for prosthetic joint infection.80 岁以上患者行至少 6 个月长程抑制性抗生素治疗用于人工关节感染的转归。
Int J Infect Dis. 2014 Dec;29:184-9. doi: 10.1016/j.ijid.2014.09.012. Epub 2014 Oct 30.
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Ann Clin Microbiol Antimicrob. 2017 Oct 4;16(1):68. doi: 10.1186/s12941-017-0243-8.
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Clin Infect Dis. 2013 Jan;56(1):e1-e25. doi: 10.1093/cid/cis803. Epub 2012 Dec 6.
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