Stelmach G E, Garcia-Colera A, Martin Z E
Motor Behavior Laboratory, University of Wisconsin-Madison 53706.
J Neurol. 1989 Oct;236(7):406-10. doi: 10.1007/BF00314899.
An experiment was performed which examined movement planning and force transition control in six patients with Parkinson's disease (PD) during a sequence of five finger taps at either a fast (200 ms) or slow (600 ms) temporal speed. The patients acted as their own controls and performed finger taps under three task conditions: (1) where all taps had to be of the same force intensity: no stress; (2) where it was known that one of the taps had to be executed with an augmented force: stress simple reaction time (SRT); and (3) where it was not known prior to initiation which one of the taps was to be more forcefully produced: stress choice reaction time (CRT). Reaction time data revealed a between-condition effect where stress SRT was faster than stress CRT and no stress was faster than both. Under both speed conditions, the interval after the stressed tap was profoundly lengthened. It was found that the lengthening was due to increases in both lift and dwell times for the slow tapping rate. In contrast, at the fast tapping rate, proportionately more of the interval increase was due to the increase in lift time. These findings suggest that patients with Parkinson's disease, when performing under a motor program mode, have difficulty in initiating a sequence and making a transition to lighter force levels after a stressed tap.
进行了一项实验，该实验检测了6名帕金森病（PD）患者在以快速（200毫秒）或慢速（600毫秒）的时间速度进行连续5次手指敲击过程中的运动规划和力转换控制。患者作为自身对照，在三种任务条件下进行手指敲击：（1）所有敲击必须具有相同的力强度：无压力；（2）已知其中一次敲击必须用增强的力执行：压力简单反应时间（SRT）；（3）在开始之前不知道哪一次敲击要更用力地进行：压力选择反应时间（CRT）。反应时间数据显示了一种条件间效应，即压力SRT比压力CRT快，且无压力比两者都快。在两种速度条件下，受压力敲击后的间隔都显著延长。结果发现，延长是由于慢敲击速率下抬起时间和停留时间的增加。相比之下，在快敲击速率下，间隔增加的比例更多是由于抬起时间的增加。这些发现表明，帕金森病患者在运动程序模式下执行任务时，在启动序列以及在受压力敲击后向较轻力水平转换方面存在困难。
