Kachhawa J P, Kumar Surender, Sharma Ankita, Singh A P, Ahuja Anil
Department of Clinical Veterinary Medicine, Ethics and Jurisprudence, College of Veterinary & Animal Science, Rajasthan University of Veterinary and Animal Sciences, Bikaner - 334 001, Rajasthan, India.
Veterinary Hospital, Haripura, Hanumangarh, Rajasthan, India.
Vet World. 2016 Dec;9(12):1381-1385. doi: 10.14202/vetworld.2016.1381-1385. Epub 2016 Dec 7.
The aim was to determine hemato-biochemical alterations and to determine the better treatment of theileriosis in naturally infected calves.
A total of 74 Holstein crossbred calves below 6 months of age, of either sex were included for present investigation in Bikaner. Based on the clinical examinations and laboratory results, 20 calves included for hemato-biochemical studies (before and after treatment) and divided into two groups (having 10 calves each).
The clinical examination of these calves revealed weakness, ticks infestations, high fever above 104°F, pronounced swelling of prescapular, prefemoral, parotid lymph nodes, loss of elasticity of skin, anemia, lacrimal discharges, pulpy cornea, tachycardia, and dyspnea. There was highly significant decrease (p<0.01) in hemoglobin, total erythrocyte count, packed cell volume and total leukocyte count, serum glucose, total protein, globulin and albumin level and highly significant increase in aspartate aminotransferase and alanine aminotransferase level as compared to healthy control animals in Group I and II. The animals of Group II treated with buparvaquone along with single blood transfusion shows better recovery then animals of Group I treated with bupavaqone and hematinic.
Significant changes were found in hemato-biochemical parameters in theileria affected calves before treatment as compare to healthy control calves. Significant improvement was observed in hemato-biochemical parameters in buparvaquone and single blood transfusion treated calves as compare to another group, so it is concluded that buparvaquone and single blood transfusion is better combination for treatment of theileriosis.
本研究旨在确定自然感染泰勒虫病的犊牛血液生化指标的变化，并确定更好的治疗方法。
本研究纳入了比卡内尔地区74头6月龄以下的荷斯坦杂交犊牛，不限性别。根据临床检查和实验室结果，选取20头犊牛进行血液生化指标研究（治疗前后），并分为两组（每组10头）。
这些犊牛的临床检查显示出虚弱、蜱虫感染、体温高于104°F的高热、肩胛前、股前、腮腺淋巴结明显肿大、皮肤弹性丧失、贫血、泪液分泌、角膜软化、心动过速和呼吸困难。与I组和II组的健康对照动物相比，血红蛋白、红细胞总数、红细胞压积和白细胞总数、血清葡萄糖、总蛋白、球蛋白和白蛋白水平显著降低（p<0.01），天冬氨酸转氨酶和丙氨酸转氨酶水平显著升高。II组用丁萘脒和单次输血治疗的动物比I组用丁萘脒和补血药治疗的动物恢复得更好。
与健康对照犊牛相比，感染泰勒虫病的犊牛在治疗前血液生化指标有显著变化。与另一组相比，用丁萘脒和单次输血治疗的犊牛血液生化指标有显著改善，因此得出结论，丁萘脒和单次输血是治疗泰勒虫病的更好组合。
