营养物质作为多囊卵巢综合征代谢紊乱的新型治疗方法。

Mansour Asieh, Hosseini Saeed, Larijani Bagher, Mohajeri-Tehrani Mohammad Reza

Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology, Research Institute Shahid Beheshti University of Medical Science, Tehran, Iran; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

EXCLI J. 2016 Sep 5;15:551-564. doi: 10.17179/excli2016-422. eCollection 2016.

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women. This disease is characterized by infertility, menstrual dysfunction, and hyperandrogenism. Also, PCOS is often associated with hyperlipidemia and impaired glucose tolerance, conditions that are associated with cardiovascular disorder, type 2 diabetes, cancer and hypertension. Evidence supports that some nutrients may affect the hormonal and metabolic disturbances of PCOS. Here in this study, we aimed to review the available literature that assessed the nutrients such as inostol, isoflavonids, resveratrol, vitamin D, and PUFA (polyunsaturated fatty acids), known to influence the hormonal and metabolic disturbances of PCOS, along with the strategies and future directions of nutrient supplementations in such patients.

多囊卵巢综合征（PCOS）是女性中最常见的内分泌紊乱疾病之一。这种疾病的特征是不孕、月经功能紊乱和雄激素过多。此外，PCOS常与高脂血症和糖耐量受损有关，这些情况与心血管疾病、2型糖尿病、癌症和高血压相关。有证据支持某些营养素可能会影响PCOS的激素和代谢紊乱。在本研究中，我们旨在综述现有文献，这些文献评估了已知会影响PCOS激素和代谢紊乱的营养素，如肌醇、异黄酮、白藜芦醇、维生素D和多不饱和脂肪酸（PUFA），以及此类患者营养补充的策略和未来方向。