Jacob Sajish, Patil Sadanand I
Memphis Neurology, 1407 Union Avenue, No. 1400, Memphis, TN 38014, USA.
Baptist Cancer Center, 6029 Walnut Grove Rd, No. 300, Memphis, TN 38120, USA.
Case Rep Med. 2016;2016:3015947. doi: 10.1155/2016/3015947. Epub 2016 Dec 21.
Chronic myelogenous leukemia (CML) blast crisis is an ominous clinical event that is challenging to treat. This can develop at extramedullary sites rarely and is defined as the infiltration of blasts outside the bone marrow irrespective of proliferation of blasts within the bone marrow. We aim to report an unusual clinical presentation characterized by Horner's syndrome, ipsilateral arm weakness, and cervical lymphadenopathy as the first signs of extramedullary blast crisis in a CML patient. To the best of our knowledge, the extramedullary locations involving the brachial plexus along with cervicothoracic paraspinal chloroma have not been previously reported in the literature.
慢性粒细胞白血病（CML）急变期是一种预后不良的临床事件，治疗颇具挑战性。这种情况很少在髓外部位发生，其定义为骨髓外原始细胞浸润，而不论骨髓内原始细胞的增殖情况。我们旨在报告一例CML患者出现的不寻常临床表现，以霍纳综合征、同侧手臂无力和颈部淋巴结肿大作为髓外急变期的首发症状。据我们所知，此前文献中尚未报道过涉及臂丛神经以及颈胸段椎旁绿色瘤的髓外部位。
