Serafini Gianluca, Engel-Yeger Batya, Vazquez Gustavo H, Pompili Maurizio, Amore Mario
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, Section of Psychiatry, University of Genoa, Genoa, Italy.
Department of Occupational Therapy, Faculty of Social Welfare and Health Sciences, University of Haifa, Israel.
Psychiatry Investig. 2017 Jan;14(1):51-57. doi: 10.4306/pi.2017.14.1.51. Epub 2016 Dec 29.
Longer duration of untreated illness, longer duration of current episode, and the severity of medication side effects may negatively impact on the perceived disability and psychosocial impairment of patients with major affective and anxiety disorders. Studies also suggested the involvement of sensory perception in emotional and psychopathological processes. The present study aimed to examine the relationship between Sensory Processing Disorders (SPD), duration of untreated illness and current illness episode, and the severity of side effects related to psychoactive medications.
The sample included 178 participants with an age ranging from 17 to 85 years (mean=53.84±15.55). Participants were diagnosed with unipolar Major Depressive Disorder (MDD) (50%), Bipolar Disorder (BD) (33.7%), and Anxiety disorders (16.3%). They completed a socio-demographic questionnaire, the Udvalg for Kliniske Undersøgelser (UKU), and Adolescent/Adult Sensory Profile (AASP) questionnaire.
Longer duration of current episode correlated with greater registration of sensory input and lower avoidance from sensory input among unipolar patients; with lower registration of sensory input, and higher tendency for sensory sensitivity/avoidance among bipolar participants; with lower sensory sensitivity/avoidance among anxiety participants, respectively. Also, mean UKU total scores correlated with lower sensory sensitivity among bipolar individuals.
SPD expressed in either hypo/hyper sensitivity may serve to clinically characterize subjects with major affective and anxiety disorders.
未治疗疾病的持续时间更长、当前发作的持续时间更长以及药物副作用的严重程度可能会对重度情感障碍和焦虑症患者的感知残疾和心理社会损害产生负面影响。研究还表明感觉知觉参与了情绪和精神病理过程。本研究旨在探讨感觉加工障碍(SPD)、未治疗疾病的持续时间和当前疾病发作以及精神活性药物相关副作用的严重程度之间的关系。
样本包括178名年龄在17至85岁之间的参与者(平均=53.84±15.55)。参与者被诊断为单相重度抑郁症(MDD)(50%)、双相情感障碍(BD)(33.7%)和焦虑症(16.3%)。他们完成了一份社会人口统计学问卷、临床检查量表(UKU)和青少年/成人感觉概况(AASP)问卷。
当前发作持续时间较长与单相患者中感觉输入的更高记录和对感觉输入的更低回避相关;与双相情感障碍参与者中感觉输入的更低记录以及感觉敏感/回避的更高倾向相关;分别与焦虑症参与者中更低的感觉敏感/回避相关。此外,双相情感障碍个体的UKU总分均值与更低的感觉敏感性相关。
以低敏/高敏形式表现的SPD可能有助于对重度情感障碍和焦虑症患者进行临床特征描述。