Gudza-Mugabe Muchaneta, Magwenzi Marcelyn T, Mujuru Hilda A, Bwakura-Dangarembizi Mutsa, Robertson Valerie, Aiken Alexander M
National Microbiology Reference Laboratory, Harare Central Hospital, Harare, Zimbabwe.
Department of Medical Microbiology, University of Zimbabwe-College of Health Sciences, Harare, Zimbabwe.
Antimicrob Resist Infect Control. 2017 Jan 11;6:8. doi: 10.1186/s13756-016-0166-8. eCollection 2017.
We assessed bacterial contamination of hands of adults present in paediatric wards in two tertiary-care hospitals in Harare, Zimbabwe and the microbiologic efficacy of locally-manufactured alcohol-based hand rub (ABHR). During unannounced visits, samples were collected using hand-print and hand-rinse methods. Samples were collected from 152 individuals (16 nurses, 10 doctors, 28 students, 86 parents/guardians, 12 others). Contamination of hands with Gram-negative bacteria was found in 91% of adults tested with a mean of 14.6 CFU (hand-rinse method; IQR 3-65), representing a high risk for transmission of pathogens potentially leading to nosocomial infections. A single application of ABHR under controlled conditions achieved an average of 82% (or 0.72 log) reduction in detectable counts. Amongst 49 isolates from hands, 53% were resistant to gentamicin and 63% were resistant to cefpodoxime. Use of ABHR represents an attractive intervention for reducing nosocomial infections in this setting.
我们评估了津巴布韦哈拉雷两家三级护理医院儿科病房中成人手部的细菌污染情况，以及当地生产的酒精基洗手液（ABHR）的微生物学功效。在突击检查期间，采用手印和手洗方法采集样本。样本取自152人（16名护士、10名医生、28名学生、86名家长/监护人、12名其他人员）。在接受检测的91%的成年人中发现手部被革兰氏阴性菌污染，平均菌落形成单位（CFU）为14.6（手洗方法；四分位距3 - 65），这表明存在病原体传播导致医院感染的高风险。在受控条件下单次使用ABHR可使可检测菌数平均减少82%（或0.72对数）。在从手部分离出的49株菌株中，53%对庆大霉素耐药，63%对头孢泊肟耐药。在这种情况下，使用ABHR是一种有吸引力的减少医院感染的干预措施。
