Flerlage Jamie E, Kelly Kara M, Beishuizen Auke, Cho Steve, De Alarcon Pedro A, Dieckmann Ute, Drachtman Richard A, Hoppe Bradford S, Howard Scott C, Kaste Sue C, Kluge Regine, Kurch Lars, Landman-Parker Judith, Lewis Jocelyn, Link Michael P, McCarten Kathleen, Punnett Angela, Stoevesandt Dietrich, Voss Stephan D, Wallace William Hamish, Mauz-Körholz Christine, Metzger Monika L
Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Roswell Park Cancer Institute, University of Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York.
Pediatr Blood Cancer. 2017 Jul;64(7). doi: 10.1002/pbc.26421. Epub 2017 Jan 18.
International harmonization of staging evaluation and response criteria is needed for childhood, adolescence, and young adulthood Hodgkin lymphoma. Two Hodgkin lymphoma protocols from cooperative trials in Europe and North America were compared for areas in need of harmonization, and an evidence-based approach is currently underway to harmonize staging and response evaluations with a goal to enhance comparisons, expedite identification of effective therapies, and aid in the approval process for new agents by regulatory agencies.
儿童、青少年和青年霍奇金淋巴瘤需要进行分期评估和反应标准的国际协调。对欧洲和北美的两项合作试验中的霍奇金淋巴瘤方案在需要协调的方面进行了比较,目前正在采用循证方法来协调分期和反应评估,目标是加强比较、加快有效疗法的识别,并协助监管机构进行新药物的审批过程。