Heath D, Khan Q
Department of Pathology, University of Liverpool, U.K.
J Pathol. 1989 Sep;159(1):29-34. doi: 10.1002/path.1711590109.
The incidence of focal chronic thyroiditis and chronic carotid glomitis was studied by histological examination in 50 subjects over the age of 50 years coming to necropsy. The two conditions appear to be distinct, affecting different age groups. Focal chronic thyroiditis occurred as early as the sixth decade and was found on its own in 34 per cent of subjects. Chronic carotid glomitis was characteristic of the eighth and ninth decades and occurred on its own in 14 per cent of subjects. In a further 12 per cent, thyroiditis and glomitis co-existed. Chronic carotid glomitis has the same histological features as auto-immune thyroiditis, the infiltrate being composed of aggregates of lymphocytes and plasma cells, raising the possibility that it, too, has a basis in auto-immunity. The antigenic stimulus for the auto-immunity in the carotid bodies may be senescent nerve fibrils.
通过组织学检查，对50例50岁以上接受尸检的受试者进行了局灶性慢性甲状腺炎和慢性颈动脉体炎发病率的研究。这两种病症似乎是不同的，影响不同的年龄组。局灶性慢性甲状腺炎最早出现在60岁左右，在34%的受试者中单独出现。慢性颈动脉体炎是80岁和90岁人群的特征，在14%的受试者中单独出现。另有12%的受试者中，甲状腺炎和颈动脉体炎并存。慢性颈动脉体炎具有与自身免疫性甲状腺炎相同的组织学特征，浸润物由淋巴细胞和浆细胞聚集而成，这增加了其也有自身免疫基础的可能性。颈动脉体自身免疫的抗原刺激可能是衰老的神经纤维。
