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基于硅光电倍增管的飞行时间和相互作用深度正电子发射断层扫描的单传输线读出方法。

Single transmission-line readout method for silicon photomultiplier based time-of-flight and depth-of-interaction PET.

作者信息

Ko Guen Bae, Lee Jae Sung

机构信息

Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul 03080, Korea. Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.

出版信息

Phys Med Biol. 2017 Mar 21;62(6):2194-2207. doi: 10.1088/1361-6560/aa5a44. Epub 2017 Jan 18.

Abstract

We propose a novel single transmission-line readout method for whole-body time-of-flight positron emission tomography applications, without compromising on performance. The basic idea of the proposed multiplexing method is the addition of a specially prepared tag signal ahead of the scintillation pulse. The tag signal is a square pulse that encodes photon arrival time and channel information. The 2D position of a silicon photomultiplier (SiPM) array is encoded by the specific width and height of the tag signal. A summing amplifier merges the tag and scintillation signals of each channel, and the final output signal can be acquired with a one-channel digitizer. The feasibility and performance of the proposed method were evaluated using a 1:1 coupled detector consisting of 4  ×  4 array of LGSO crystals and 16 channel SiPM. The sixteen 3 mm LGSO crystals were clearly separated in the crystal-positioning map with high reliability. The average energy resolution and coincidence resolving time were 11.31  ±  0.55% and 264.7  ±  10.7 ps, respectively. We also proved that the proposed method does not degrade timing performance with increasing multiplexing ratio. The two types of LGSO crystals (LGSO and LGSO) in phoswich detector were also clearly identified with the high-reliability using pulse shape discrimination, thanks to the well-preserved pulse shape information. In conclusion, the proposed multiplexing method allows decoding of the 3D interaction position of gamma rays in the scintillation detector with single-line readout.

摘要

我们提出了一种新颖的单传输线读出方法,用于全身飞行时间正电子发射断层扫描应用,且不影响性能。所提出的复用方法的基本思想是在闪烁脉冲之前添加一个特别准备的标记信号。该标记信号是一个方波脉冲,对光子到达时间和通道信息进行编码。硅光电倍增管(SiPM)阵列的二维位置由标记信号的特定宽度和高度编码。求和放大器合并每个通道的标记信号和闪烁信号,最终输出信号可通过单通道数字化仪获取。使用由4×4阵列的LGSO晶体和16通道SiPM组成的1:1耦合探测器评估了所提方法的可行性和性能。在晶体定位图中,十六个3毫米的LGSO晶体以高可靠性清晰分离。平均能量分辨率和符合分辨时间分别为11.31±0.55%和264.7±10.7皮秒。我们还证明了所提方法不会随着复用率的增加而降低定时性能。由于脉冲形状信息得到良好保留,通过脉冲形状鉴别,磷光体探测器中的两种LGSO晶体(LGSO和LGSO)也以高可靠性清晰识别。总之,所提出的复用方法允许通过单线路读出对闪烁探测器中伽马射线的三维相互作用位置进行解码。

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