Qu Yan-Jing, Jin Shu-Bin, Han Xiang-Chun, Zheng Li-Qiang
The 251st Hospital of Chinese PLA - Zhangjiakou city, China.
HanDan Central Hospital - Handan city, China.
An Bras Dermatol. 2016 Nov-Dec;91(6):808-810. doi: 10.1590/abd1806-4841.20165182.
Acute localized exanthematous pustulosis is a localized variant of acute generalized exanthematous pustulosis, which is characterized by the eruption of multiple scattered pustules following drug administration. A 72-year-old woman presented with multiple erythematous pustules on her face, which had appeared two days after using cefoperazone and sodium sulbactam. Histopathological findings showed subcorneal pustules and mixed inflammatory cell infiltration in the dermis. The pustules resolved within about two weeks after the patient discontinued the antibiotics. This report discusses the case of a woman with a cutaneous drug reaction consistent with acute localized exanthematous pustulosis that occurred after cefoperazone and sodium sulbactam were administered.
急性局限性脓疱性皮疹是急性泛发性脓疱性皮疹的一种局限性变体，其特征是用药后出现多个散在的脓疱。一名72岁女性面部出现多个红斑性脓疱，这些脓疱在使用头孢哌酮舒巴坦两天后出现。组织病理学检查结果显示角层下脓疱及真皮内混合性炎症细胞浸润。患者停用抗生素后，脓疱在约两周内消退。本报告讨论了一名女性在使用头孢哌酮舒巴坦后发生符合急性局限性脓疱性皮疹的皮肤药物反应的病例。
