特比萘芬致急性泛发性发疹性脓疱病。

Acute generalized exanthematous pustulosis due to terbinafine.

机构信息

Department of Dermatology, Lewis Katz School of Medicine at Temple University Hospital, Philadelphia, Pennsylvania.

Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida.

出版信息

Dermatol Ther. 2018 Jul;31(4):e12617. doi: 10.1111/dth.12617. Epub 2018 May 21.

DOI:10.1111/dth.12617

PMID:29786933

Abstract

Acute generalized exanthematous pustulosis is a rare adverse cutaneous reaction characterized by the rapid appearance of numerous pustules arising on edematous, erythematous skin. It is commonly accompanied by fever and leukocytosis and usually resolves with discontinuation of the offending agent. Herein, acute generalized exanthematous pustulosis induced by terbinafine is described, followed by a brief review of the literature.

摘要

急性泛发性发疹性脓疱病是一种罕见的皮肤不良反应，其特征为迅速出现大量脓疱，这些脓疱出现在水肿性红斑性皮肤上。常伴有发热和白细胞增多，通常停用致病药物后可缓解。本文描述了一例由特比萘芬引起的急性泛发性发疹性脓疱病，并对文献进行了简要回顾。