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使用“肌腱桥”或“肌腱隧道”作为神经再生导管的实验研究。

An experimental study of using "tendon bridge" or "tendon tunnel" as a conduit for nerve regeneration.

作者信息

Luo Y X, Chao D C

出版信息

J Tongji Med Univ. 1989;9(2):103-6. doi: 10.1007/BF02908936.

DOI:10.1007/BF02908936
PMID:2810429
Abstract

In our experiments, a "tendon bridge" or a "tendon tunnel" was used as a conduit to repair the defect of a peripheral nerve in rabbits. A gap of about 1 cm was made on the deep peroneal nerve in each animal. In group 1, the tendon of anterior tibial muscle was isolated near the severed nerve, and a segment of half cross section of tendon was removed in ladder-shaped reversed fashion. The proximal and distal nerve stump were sutured respectively to the tendon by 11/0 atraumatic sutures under surgical microscope. In group 2, the nerve stumps were sutured to the tendon of anterior tibial muscle without cutting the tendon, but the tendon was dissected free and turned to form a tunnel wrapping the gap in between the nerve stumps. The results showed that a gap of 1 cm of the deep peroneal nerve might be repaired by both methods, but the results of using "tendon tunnel" in group 2 were much better than those of using "tendon bridge" in group 1.

摘要

在我们的实验中,使用“肌腱桥”或“肌腱隧道”作为管道来修复兔周围神经缺损。在每只动物的腓深神经上制造约1cm的间隙。在第1组中,在离断神经附近分离胫前肌肌腱,以梯形翻转方式切除一段半横截面的肌腱。在手术显微镜下,将近端和远端神经残端分别用11/0无创伤缝线缝合到肌腱上。在第2组中,不切断肌腱,将神经残端缝合到胫前肌肌腱上,但将肌腱游离并翻转形成包裹神经残端之间间隙的隧道。结果表明,两种方法均可修复1cm的腓深神经间隙,但第2组使用“肌腱隧道”的效果远优于第1组使用“肌腱桥”的效果。

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J Tongji Med Univ. 1989;9(2):103-6. doi: 10.1007/BF02908936.
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本文引用的文献

1
Autogenous vein graft as a conduit for nerve regeneration.自体静脉移植作为神经再生的导管。
Surgery. 1982 Feb;91(2):226-33.
2
Nerve regeneration through synthetic biodegradable nerve guides: regulation by the target organ.通过合成可生物降解神经导管实现的神经再生:受靶器官调节。
Plast Reconstr Surg. 1984 Aug;74(2):173-81. doi: 10.1097/00006534-198408000-00001.
3
Tropism in nerve regeneration in vivo. Attraction of regenerating axons by diffusible factors derived from cells in distal nerve stumps of transected peripheral nerves.
体内神经再生中的趋向性。横断周围神经远端神经残端细胞产生的可扩散因子对再生轴突的吸引作用。
Brain Res. 1982 Dec 16;253(1-2):1-12. doi: 10.1016/0006-8993(82)90667-9.
4
Schwann cell properties. II. The identity of phagocytes in the degenerating nerve.施万细胞特性。II. 退变神经中吞噬细胞的身份。
Am J Pathol. 1974 May;75(2):395-416.