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新儿童哮喘指南介绍:对哮喘控制水平的影响。

Introduction of a new paediatric asthma guideline: Effects on asthma control levels.

机构信息

Department of Paediatric Respiratory Medicine, Maastricht University Medical Centre (MUMC+), Maastricht, The Netherlands.

Department of Paediatrics, Vie Curi Hospital, Venlo, The Netherlands.

出版信息

Pediatr Allergy Immunol. 2017 May;28(3):266-272. doi: 10.1111/pai.12697. Epub 2017 Mar 28.

Abstract

BACKGROUND

In 2008, a new national paediatric asthma management guideline based on the international Global Initiative for Asthma (GINA) guideline was launched in the Netherlands. We studied whether asthma control and treatment regimens improved after introduction of the guideline by comparing survey data before and after the guideline introduction.

METHODS

Two comparable groups of children (6-16 years) with asthma were included before (2004) and after (2013) the introduction of the guideline. Children, parents and paediatricians completed questionnaires about asthma symptoms, medication and healthcare use. Spirometry was performed.

RESULTS

Data of 209 patients were analysed. Level of asthma control did not improve between 2004 and 2013 with a proportion of (partly) controlled asthmatics of 51% in 2004 and 59% in 2013 (p = 0.28). In 2013, paediatricians characterized 76% of children as (partly) controlled, while 59% of children was (partly) controlled according to GINA criteria (p < 0.05). Step-down treatment in controlled patients was more applied by paediatricians in 2013 compared to 2004 (from 8 to 40%, p < 0.05). Step-up treatment in uncontrolled patients did not improve.

CONCLUSIONS

Asthma control did not improve after the introduction of the new guideline. Compared to 2004, an improvement was observed in step-down treatment in patients with controlled disease.

摘要

背景

2008 年,荷兰推出了一项基于国际哮喘倡议(GINA)指南的新国家儿科哮喘管理指南。我们通过比较指南推出前后的调查数据,研究了指南推出后哮喘控制和治疗方案是否有所改善。

方法

纳入了指南推出前(2004 年)和推出后(2013 年)两组年龄在 6-16 岁的具有可比性的哮喘儿童。儿童、家长和儿科医生完成了关于哮喘症状、药物治疗和医疗保健使用的调查问卷,并进行了肺功能检查。

结果

共分析了 209 名患者的数据。2004 年至 2013 年间,哮喘控制水平并未改善,部分控制的哮喘患者比例为 51%(2004 年)和 59%(2013 年)(p=0.28)。2013 年,儿科医生将 76%的儿童描述为(部分)控制,而根据 GINA 标准,只有 59%的儿童(部分)控制(p<0.05)。与 2004 年相比,2013 年控制良好的患者接受降阶梯治疗的比例更高(从 8%到 40%,p<0.05)。未控制患者的升阶梯治疗并未改善。

结论

新指南推出后,哮喘控制并未改善。与 2004 年相比,控制良好患者的降阶梯治疗有所改善。

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