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GINA 标准与儿童哮喘控制测试在哮喘控制判定上的一致性。

Consistency of GINA criteria and childhood asthma control test on the determination of asthma control.

机构信息

Ankara Children's Hematology Oncology Education and Research Hospital, Department of Pediatric Allergy, Ankara, Turkey.

出版信息

Pediatr Allergy Immunol. 2012 Feb;23(1):34-9. doi: 10.1111/j.1399-3038.2011.01232.x. Epub 2011 Dec 4.

DOI:10.1111/j.1399-3038.2011.01232.x
PMID:22136557
Abstract

BACKGROUND

Reliable assessment of asthma control is essential for effective treatment. Although several methods are used to assess asthma control, it is still suboptimal all over the world. Childhood asthma control test (C-ACT) is a widely used complementary test in determining the level of asthma control in conjunction with GINA guidelines.

OBJECTIVE

To evaluate the consistency between the childhood asthma control test (C-ACT) and the Global Initiative for Asthma (GINA) guideline-based asthma control measure in children with asthma and, if present, to investigate the reasons for any discrepancy.

METHODS

Patients and their caregivers filled a C-ACT and a socioeconomic status survey before the physician visit. Asthma control level was also assessed according to GINA criteria by a pediatric allergist who was blinded to C-ACT scores.

RESULTS

The mean age of the total 314 patients was 9.0 ± 1.9 yr, ranging between 4.3 and 11.8 yr, of whom 56.1% (n = 176) were men. Regarding the study group, 54.8% of patients were controlled according to GINA, and 51.0% of patients were controlled according to C-ACT (score ≥20). There was inconsistency between GINA and C-ACT in 26.7% (84/314) of the study group when the patients were evaluated individually (κ = 0.464). There was not any significant variable that could predict the consistency and inconsistency between these methods.

CONCLUSION

Consistency between GINA and C-ACT is not as to be expected. Using only one method for determining the control level of asthma does not seem to be reliable and accurate.

摘要

背景

可靠的哮喘控制评估对于有效治疗至关重要。尽管有几种方法用于评估哮喘控制,但在全球范围内仍然不理想。儿童哮喘控制测试(C-ACT)是一种广泛使用的补充测试,与 GINA 指南一起用于确定哮喘控制水平。

目的

评估儿童哮喘控制测试(C-ACT)与基于全球哮喘倡议(GINA)指南的哮喘控制措施在哮喘儿童中的一致性,如果存在差异,还调查原因。

方法

患者及其照顾者在就诊前填写 C-ACT 和社会经济状况调查。哮喘控制水平也根据儿科过敏专家的 GINA 标准进行评估,该专家对 C-ACT 评分不知情。

结果

总共有 314 名患者的平均年龄为 9.0 ± 1.9 岁,年龄范围为 4.3 至 11.8 岁,其中 56.1%(n = 176)为男性。在研究组中,根据 GINA,54.8%的患者得到控制,根据 C-ACT(得分≥20),51.0%的患者得到控制。在单独评估时,研究组中有 26.7%(84/314)的患者在 GINA 和 C-ACT 之间存在不一致(κ=0.464)。没有任何显著变量可以预测这些方法之间的一致性和不一致性。

结论

GINA 和 C-ACT 之间的一致性不如预期。仅使用一种方法来确定哮喘的控制水平似乎不可靠和不准确。

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