Velten Deise Berger, Zandonade Eliana, Monteiro de Barros Miotto Maria Helena
Federal University of Espírito Santo, Av. Mal. Campos, 1468 - Maruípe, Vitória, ES, 29043-900, Brazil.
BMC Oral Health. 2017 Jan 20;17(1):49. doi: 10.1186/s12903-016-0331-8.
Oral complications may be observed during chemotherapy and are important side effects that may directly affect the anticancer treatment, even causing septicaemia in some cases. This research was done in order to evaluate changes in oral lesions during follow-up of children and adolescents in chemotherapy at Hospital Estadual Infantil Nossa Senhora da Glória (HEINSG).
The study design was longitudinal, 45 patients were evaluated and monitored for 1 month after the initiation of chemotherapy. Twenty-eight patients were male and 17 female, ranging from 3 months to 18 years old.
The results show an increase in the number of mucositis cases and a decrease in xerostomia cases after the initiation of treatment, and other oral lesions were also found in low numbers.
It is possible to avoid oral complications by maintaining a good oral health, and reducing infectious outbreaks. It is also feasible to obtain an early diagnosis of, and treat these oral complications, preventing them from following a more severe clinical course that may negatively affect the individual's treatment. This outcome requires the presence of a dental surgeon on the multidisciplinary cancer treatment team.
化疗期间可能会出现口腔并发症，这些并发症是重要的副作用，可能直接影响抗癌治疗，在某些情况下甚至会导致败血症。本研究旨在评估在埃斯塔杜阿尔儿童医院诺萨·塞诺拉·达·格洛里亚医院（HEINSG）接受化疗的儿童和青少年在随访期间口腔病变的变化。
研究设计为纵向研究，45例患者在化疗开始后接受了1个月的评估和监测。28例为男性，17例为女性，年龄从3个月至18岁不等。
结果显示，治疗开始后，口腔炎病例数增加，口干症病例数减少，还发现了少量其他口腔病变。
通过保持良好的口腔卫生和减少感染爆发，可以避免口腔并发症。早期诊断和治疗这些口腔并发症也是可行的，可防止其发展为更严重的临床病程，从而对个体治疗产生负面影响。这一结果需要多学科癌症治疗团队中有牙科医生。
