Fernández-Guarino M, Aboin-Gonzalez S, Ciudad Blanco C, Velázquez Tarjuelo D, Lázaro Ochayta P
Dermatology Department, Hospital Universitario Sanitas La Zarzuela, Universidad Francisco de Vitoria, Madrid, Spain.
Clin Exp Dermatol. 2017 Apr;42(3):303-305. doi: 10.1111/ced.13035. Epub 2017 Jan 23.
Pityriasis lichenoides chronica (PLC) is an infrequent dermatosis of unknown aetiology, wholse evolution and response to treatment differs between children and adults. When PLC is recalcitrant or unresponsive to topical treatment, phototherapy is one of the main treatments used. We carried out a prospective study of adult diffuse PLC treated with narrowband ultraviolet B (NB-UVB). We treated eight patients whose disease showed no response to topical therapy, and obtained a complete response rate of 88% in a mean of 23 sessions (cumulative dose 16.99 J/cm ). However, the relapse rate was 43% in the first 6 months. Our results are similar to those of other published studies but there is much variability between them in the doses applied and the number of sessions needed. Further studies are necessary to devise a protocol for NB-UVB treatment of PLC.
慢性苔藓样糠疹（PLC）是一种病因不明的罕见皮肤病，其病程演变及对治疗的反应在儿童和成人中有所不同。当PLC对局部治疗顽固不化或无反应时，光疗是主要的治疗方法之一。我们对采用窄谱中波紫外线（NB-UVB）治疗的成人播散性PLC进行了一项前瞻性研究。我们治疗了8例对局部治疗无反应的患者，平均23次治疗（累积剂量16.99 J/cm）后完全缓解率达88%。然而，前6个月的复发率为43%。我们的结果与其他已发表研究的结果相似，但在应用剂量和所需治疗次数方面存在很大差异。有必要进行进一步研究以制定PLC的NB-UVB治疗方案。
