Cogley Kimberly, Echevarria Andrea, Correa Catalina, De la Torre-Mondragón Luis
Colorectal Center for Children, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.
Pediatr Dermatol. 2017 Mar;34(2):e85-e88. doi: 10.1111/pde.13068. Epub 2017 Jan 23.
Eight children treated for severe constipation with sennosides unexpectedly developed contact burns with blisters secondary to the use of these laxatives. All patients wore diapers, and the injuries occurred overnight. To avoid this side effect, we recommend that patients treated with sennosides, especially those in diapers, receive the medication at a time that allows for bowel movements to occur during the day and not overnight.
八名使用番泻苷治疗严重便秘的儿童意外出现了因使用这些泻药继发的接触性烧伤并起水泡。所有患者都使用尿布，且损伤在夜间发生。为避免这种副作用，我们建议使用番泻苷治疗的患者，尤其是使用尿布的患者，在白天排便时而非夜间服用该药物。
