从余甘子根中分离出的两种新型抗烟草花叶病毒活性查耳酮类似物。

Two new Anti-TMV active chalconoid analogues from the root of Phyllanthus emblica.

作者信息

Yan He, Han Li Rong, Zhang Xing, Feng Jun Tao

机构信息

a Research & Development Center of Biorational Pesticide , Northwest A&F University , Yangling , China.

b College of Plant Protection , Northwest A&F University , Yangling , China.

出版信息

Nat Prod Res. 2017 Sep;31(18):2143-2148. doi: 10.1080/14786419.2017.1280487. Epub 2017 Jan 23.

DOI:10.1080/14786419.2017.1280487

PMID:28111978

Abstract

Two new chalconoid analogues, emblirol A (1) and B (2), along with three known ones (3-5), were isolated from the root of the Phyllanthus emblica L. Their structures were elucidated on the basis of spectral data. Compound 1 and 2 showed moderate anti-TMV activity with inhibition rates 79.6 and 62.1% at a concentration of 1 mg/mL, respectively.

摘要

从余甘子的根部分离出两种新的查耳酮类似物余甘醇A（1）和余甘醇B（2），以及三种已知的类似物（3 - 5）。基于光谱数据阐明了它们的结构。化合物1和2在浓度为1mg/mL时表现出中等的抗烟草花叶病毒（TMV）活性，抑制率分别为79.6%和62.1%。