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[测定患者生物样本中耶尔森菌抗原的诊断价值]

[The diagnostic value of determining Yersinia antigens in biological substrates of a patient].

作者信息

Iushchuk N D, Tseneva G Ia, Vial'ba E V

出版信息

Klin Med (Mosk). 1989 Jul;67(7):77-81.

PMID:2811220
Abstract

The authors consider the time course changes in the elimination of Yersinia antigens with biological substances in various clinical presentation of yersiniosis. Altogether 101 patients aged 15-58 have been examined. It is established that Yersinia antigens are the most frequent finding in the blood irrespective of the disease form (81-90% of cases); in the gastrointestinal pattern they are more commonly identified in the faeces (63% of cases), in generalized cases the antigens occur in the urine and faeces of patients in 43 and 49% of cases, respectively. Evaluation of changes in elimination of Yersinia antigens from the body provides a good evidence for case prognosis which is of particular importance for potential cases with protracted and chronic forms of the disease as well as for evaluation of the antibacterial treatment efficacy.

摘要

作者们研究了耶尔森菌病不同临床表现中,耶尔森菌抗原随生物物质排出体外的时间进程变化。共检查了101名年龄在15至58岁之间的患者。结果表明,无论疾病形式如何,耶尔森菌抗原在血液中最为常见(81%-90%的病例);在胃肠道型中,它们更常见于粪便中(63%的病例),在全身性病例中,抗原分别出现在43%和49%的患者尿液和粪便中。评估耶尔森菌抗原从体内排出的变化情况,可为病例预后提供有力证据,这对于疾病迁延不愈和慢性形式的潜在病例以及评估抗菌治疗效果尤为重要。

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