From the Departments of *Nuclear Medicine & PET Centre, and †Pathology, Aarhus University Hospital, Aarhus, Denmark.
Clin Nucl Med. 2017 Apr;42(4):e214-e215. doi: 10.1097/RLU.0000000000001542.
We present a case of a subcutaneous process in the abdominal wall with high prostate-specific membrane antigen (PSMA) activity on Ga-PSMA PET/CT. Histology demonstrated a benign lobular capillary hemangioma with a high vascular density, with highly PSMA-positive endothelial cells. It is well known that PSMA is expressed in different tissue, including neovasculature in various malignant tumors, and the knowledge is rapidly evolving as new discoveries appear.
我们报告了一例 Ga-PSMA PET/CT 示前列腺特异膜抗原(PSMA)活性增高的腹壁皮下病变。组织学表现为良性小叶状毛细血管血管瘤,血管密度高,PSMA 阳性的内皮细胞丰富。众所周知,PSMA 在不同组织中均有表达,包括各种恶性肿瘤的新生血管,随着新发现的出现,其知识也在迅速发展。