He Jiangnan, Lu Lina, He Xiangui, Xu Xian, Du Xuan, Zhang Bo, Zhao Huijuan, Sha Jida, Zhu Jianfeng, Zou Haidong, Xu Xun
Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai, China.
Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China.
PLoS One. 2017 Jan 23;12(1):e0170030. doi: 10.1371/journal.pone.0170030. eCollection 2017.
To report calculated crystalline lens power and describe the distribution of ocular biometry and its association with refractive error in older Chinese adults.
Random clustering sampling was used to identify adults aged 50 years and above in Xuhui and Baoshan districts of Shanghai. Refraction was determined by subjective refraction that achieved the best corrected vision based on monocular measurement. Ocular biometry was measured by IOL Master. The crystalline lens power of right eyes was calculated using modified Bennett-Rabbetts formula.
We analyzed 6099 normal phakic right eyes. The mean crystalline lens power was 20.34 ± 2.24D (range: 13.40-36.08). Lens power, spherical equivalent, and anterior chamber depth changed linearly with age; however, axial length, corneal power and AL/CR ratio did not vary with age. The overall prevalence of hyperopia, myopia, and high myopia was 48.48% (95% CI: 47.23%-49.74%), 22.82% (95% CI: 21.77%-23.88%), and 4.57% (95% CI: 4.05-5.10), respectively. The prevalence of hyperopia increased linearly with age while lens power decreased with age. In multivariate models, refractive error was strongly correlated with axial length, lens power, corneal power, and anterior chamber depth; refractive error was slightly correlated with best corrected visual acuity, age and sex.
Lens power, hyperopia, and spherical equivalent changed linearly with age; Moreover, the continuous loss of lens power produced hyperopic shifts in refraction in subjects aged more than 50 years.
报告计算得出的晶状体屈光度，并描述老年中国成年人眼部生物测量参数的分布及其与屈光不正的关系。
采用随机整群抽样法在上海徐汇区和宝山区选取50岁及以上的成年人。通过基于单眼测量实现最佳矫正视力的主观验光来确定屈光状态。使用IOL Master测量眼部生物参数。采用改良的Bennett-Rabbetts公式计算右眼的晶状体屈光度。
我们分析了6099只正常有晶状体的右眼。平均晶状体屈光度为20.34±2.24D（范围：13.40 - 36.08）。晶状体屈光度、等效球镜度和前房深度随年龄呈线性变化；然而，眼轴长度、角膜屈光度和眼轴/晶状体厚度比不随年龄变化。远视、近视和高度近视的总体患病率分别为48.48%（95%CI：47.23% - 49.74%）、22.82%（95%CI：21.77% - 23.88%）和4.57%（95%CI：4.05 - 5.10）。远视患病率随年龄呈线性增加，而晶状体屈光度随年龄降低。在多变量模型中，屈光不正与眼轴长度、晶状体屈光度、角膜屈光度和前房深度密切相关；屈光不正与最佳矫正视力、年龄和性别略有相关。
晶状体屈光度、远视和等效球镜度随年龄呈线性变化；此外，50岁以上人群晶状体屈光度的持续下降导致屈光向远视偏移。
