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中国老年人群的屈光不正与生物测量:荔湾眼研究

Refractive error and biometry in older Chinese adults: the Liwan eye study.

作者信息

He Mingguang, Huang Wenyong, Li Yuetao, Zheng Yingfeng, Yin Qiuxia, Foster Paul J

机构信息

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

出版信息

Invest Ophthalmol Vis Sci. 2009 Nov;50(11):5130-6. doi: 10.1167/iovs.09-3455. Epub 2009 Jun 24.

Abstract

PURPOSE

To assess the prevalence of refractive error and describe the distribution of ocular biometry and its association with refraction in adult Chinese.

METHODS

Random clustering sampling was used to identify adults aged > or = 50 years in Liwan District, Guangzhou. Refraction was determined by subjective refraction that achieved the best corrected vision based on monocular measurement. Ocular biometry was measured by A-mode ultrasound using a handheld applanation probe.

RESULTS

Among 1405 participants in the study, data from 1269 phakic right eyes were available for analysis. The prevalence of myopia (SE < -0.5 D), hyperopia (SE > +0.5 D), and astigmatism (cylinder > 0.75 D) was 32.3% (95% confidence interval [CI], 27.8%-34.6%), 40.0% (95% CI, 37.3%-42.7%), and 48.3% (95% CI, 45.6%-51.1%), respectively. The spherical equivalent tended to become hyperopic at 60 years and shifted toward myopia at 75 years. Axial length did not change with age but was consistently shorter in women. Lens thickness increased with age and tended to be greater in women.

CONCLUSIONS

The prevalence of myopia and biometric distribution in this urban Chinese cohort are similar to those observed in Singaporean Chinese but greater than in Mongolians and Europeans. Further studies are needed to clarify the role of environmental factors in the myopia rates.

摘要

目的

评估屈光不正的患病率,并描述中国成年人眼部生物测量参数的分布及其与屈光的关系。

方法

采用随机整群抽样法在广州荔湾区选取年龄≥50岁的成年人。通过基于单眼测量获得最佳矫正视力的主观验光法确定屈光状态。使用手持压平探头通过A超测量眼部生物参数。

结果

在1405名研究参与者中,1269只具有晶状体的右眼数据可用于分析。近视(等效球镜度<-0.5D)、远视(等效球镜度>+0.5D)和散光(柱镜度>0.75D)的患病率分别为32.3%(95%置信区间[CI],27.8%-34.6%)、40.0%(95%CI,37.3%-42.7%)和48.3%(95%CI,45.6%-51.1%)。等效球镜度在60岁时趋于远视,在75岁时转向近视。眼轴长度不随年龄变化,但女性始终较短。晶状体厚度随年龄增加,女性往往更厚。

结论

该中国城市队列中的近视患病率和生物测量参数分布与新加坡华人相似,但高于蒙古人和欧洲人。需要进一步研究以阐明环境因素在近视率中的作用。

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