Gross-Isseroff R, Ophir D, Marshak G, Ganchrow J R, Beizer M, Lancet D
Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel.
Laryngoscope. 1989 Nov;99(11):1165-6. doi: 10.1288/00005537-198911000-00011.
Results of olfactory function tests (threshold determination and odor identification) in three cases of bilateral and one case of unilateral choanal atresia are reported. All four patients underwent successful repair of choanal atresia at relatively advanced ages (8 to 31 years). Test results showed that patients who had suffered from bilateral atresia had permanent olfactory deficits, while the patient who had suffered from unilateral atresia appeared to have normal olfactory acuity. Although these results should be interpreted with caution due to the small number of cases examined, they suggest the possibility that early sensory exposure might be needed for the normal development of central olfactory functions in analogy to the visual system.
报告了3例双侧和1例单侧后鼻孔闭锁患者的嗅觉功能测试结果（阈值测定和气味识别）。所有4例患者均在相对较大年龄（8至31岁）时成功进行了后鼻孔闭锁修复术。测试结果显示，双侧闭锁患者存在永久性嗅觉缺陷，而单侧闭锁患者的嗅觉敏锐度似乎正常。尽管由于所检查的病例数量较少，这些结果应谨慎解读，但它们表明，类似于视觉系统，中枢嗅觉功能的正常发育可能需要早期的感觉暴露。
