Gou Chao-Qin, Gao Jing, Wu Chen-Xi, Bai Ding-Xi, Mou Hong-Yuan, Hou Xiao-Lin, Zhao Xia
Chengdu University of Traditional Chinese Medicine, No. 37 Shierqiao Road, Jinniu District, Chengdu, Sichuan 610075, China.
Evid Based Complement Alternat Med. 2016;2016:6706901. doi: 10.1155/2016/6706901. Epub 2016 Dec 28.
Primary dysmenorrhea (PD) is one of the most common diseases in gynecology at present. Some clinical trials have reported the effects of moxibustion and confirmed temporal factors are the important elements influencing the efficacy of moxibustion. However, no systematic review has yet been conducted. In this study, we assessed the effects of moxibustion in patients with PD enrolled in randomized controlled trials (RCTs) and the difference among different intervention times to start moxibustion. We extracted data for studies searched from 10 electronic databases and evaluated the methodological quality of the included studies. We discussed three outcomes: effective rate, pain remission, and the level of PGF2 in serum. Current clinical researches showed that, compared with nonmoxibustion treatments for PD, moxibustion leads to higher effective rate and lower level of PGF2 in serum. However, there was no difference in using moxibustion to treat PD at different intervention times. Based on the theory of Chinese medicine and the results of this study, choosing 5 ± 2 days before menstruation to start moxibustion can achieve good efficacy for PD patients. However, more high-quality RCTs are needed to confirm the conclusions.
原发性痛经（PD）是目前妇科最常见的疾病之一。一些临床试验报告了艾灸的效果，并证实时间因素是影响艾灸疗效的重要因素。然而，尚未进行系统评价。在本研究中，我们评估了艾灸对纳入随机对照试验（RCT）的PD患者的疗效以及开始艾灸的不同干预时间之间的差异。我们从10个电子数据库中提取检索到的研究数据，并评估纳入研究的方法学质量。我们讨论了三个结果：有效率、疼痛缓解和血清中PGF2水平。目前的临床研究表明，与PD的非艾灸治疗相比，艾灸可提高有效率并降低血清中PGF2水平。然而，在不同干预时间使用艾灸治疗PD并无差异。基于中医理论和本研究结果，选择月经前5±2天开始艾灸对PD患者可取得良好疗效。然而，需要更多高质量的RCT来证实这些结论。
