Yang Yiting, Ma Chung Wah, Yang Yide, Wang Xiaoling, Lin Xiaoliang, Fu Lianguo, Wang Shuo, Yang Zhongping, Wang Zhenghe, Meng Xiangkun, Ma Dongmei, Ma Rui, Ma Jun
Research & Development Centre, Infinitus (China) Company Ltd., Guangzhou, China.
Institute of Child and Adolescent Health, School of Public Health, Peking University Health Science Center, Beijing, China.
Evid Based Complement Alternat Med. 2017;2017:1239404. doi: 10.1155/2017/1239404. Epub 2017 Jan 1.
Overweight or obese adults aged 20~55 years and living in Beijing more than one year were randomly divided into different management groups. A one-year integrated health management intervention was applied in the health management groups. The physical indicators and metabolic indicators changed after one-year intervention on the overweight and obese adults. The annual reduction of the physical indicators was significant in all groups ( < 0.05) except the weight loss in the placebo + general management group. The health management and the dietary supplement have statistically significant ( < 0.001, < 0.001) effects on the annual reduction of these indicators and interactive effect between them was found on some of these indicators such as bodyweight, body mass index (BMI), body fat ratio (BFR), and hipline ( < 0.05). The dietary supplement + health management group had the best annual reduction effects for the indicators among the groups. Integrated health management interventions including both dietary supplements intervention and health management could improve metabolic indicators in overweight and obese adults together with the physical indicators, suggesting the intermediated role of metabolic indictors in controlling obesity.
年龄在20至55岁之间、居住在北京一年以上的超重或肥胖成年人被随机分为不同的管理组。对健康管理组实施了为期一年的综合健康管理干预。对超重和肥胖成年人进行一年干预后，身体指标和代谢指标发生了变化。除安慰剂+一般管理组的体重减轻外，所有组的身体指标年度下降均具有显著性（<0.05）。健康管理和膳食补充剂对这些指标的年度下降具有统计学显著性影响（<0.001，<0.001），并且在体重、体重指数（BMI）、体脂率（BFR）和臀围等一些指标上发现它们之间存在交互作用（<0.05）。膳食补充剂+健康管理组在各小组中对这些指标的年度下降效果最佳。包括膳食补充剂干预和健康管理在内的综合健康管理干预可以同时改善超重和肥胖成年人的代谢指标以及身体指标，这表明代谢指标在控制肥胖中起中介作用。
