Gholipour Baradari Afshin, Sharifi Hassan, Firouzian Abolfazl, Daneshiyan Maryam, Aarabi Mohsen, Talebiyan Kiakolaye Yaser, Nouraei Seyed Mahmood, Zamani Kiasari Alieh, Habibi Mohammad Reza, Emami Zeydi Amir, Sadeghi Faegheh
Department of Anesthesiology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Iranshahr University of Medical Sciences, Iranshahr, Iran.
Scientifica (Cairo). 2016;2016:7379325. doi: 10.1155/2016/7379325. Epub 2016 Dec 25.
. The sequential organ failure assessment (SOFA) score has been recommended to triage critically ill patients in the intensive care unit (ICU). This study aimed to compare the performance of our proposed MSOFA and original SOFA scores in predicting ICU mortality. . This prospective observational study was conducted on 250 patients admitted to the ICU. Both tools scores were calculated at the beginning, 24 hours of ICU admission, and 48 hours of ICU admission. Diagnostic odds ratio and receiver operating characteristic (ROC) curve were used to compare the two scores. . MSOFA and SOFA predicted mortality similarly with an area under the ROC curve of 0.837, 0.992, and 0.977 for MSOFA 1, MSOFA 2, and MSOFA 3, respectively, and 0.857, 0.988, and 0.988 for SOFA 1, SOFA 2, and SOFA 3, respectively. The sensitivity and specificity of MSOFA 1 in cut-off point 8 were 82.9% and 68.4%, respectively, MSOFA 2 in cut-off point 9.5 were 94.7% and 97.1%, respectively, and MSOFA 3 in cut-off point of 9.3 were 97.4% and 93.1%, respectively. There was a significant positive correlation between the MSOFA 1 and the SOFA 1 (: 0.942), 24 hours (: 0.972), and 48 hours (: 0.960). . The proposed MSOFA and the SOFA scores had high diagnostic accuracy, sensitivity, and specificity for predicting mortality.
序贯器官衰竭评估（SOFA）评分已被推荐用于对重症监护病房（ICU）的危重症患者进行分诊。本研究旨在比较我们提出的改良序贯器官衰竭评估（MSOFA）评分和原始SOFA评分在预测ICU死亡率方面的表现。 这项前瞻性观察性研究对250名入住ICU的患者进行。在入住ICU开始时、入住24小时和48小时时计算两种工具的评分。使用诊断比值比和受试者工作特征（ROC）曲线来比较这两个评分。 MSOFA和SOFA对死亡率的预测相似，MSOFA 1、MSOFA 2和MSOFA 3的ROC曲线下面积分别为0.837、0.992和0.977，SOFA 1、SOFA 2和SOFA 3的ROC曲线下面积分别为0.857、0.988和0.988。MSOFA 1在截断点为8时的敏感性和特异性分别为82.9%和68.4%，MSOFA 2在截断点为9.5时的敏感性和特异性分别为94.7%和97.1%，MSOFA 3在截断点为9.3时的敏感性和特异性分别为97.4%和93.1%。MSOFA 1与SOFA 1（r = 0.942）、24小时（r = 0.972）和48小时（r = 0.960）之间存在显著正相关。 提出的MSOFA评分和SOFA评分在预测死亡率方面具有较高的诊断准确性、敏感性和特异性。
