Liu Li, Liu Dong-Xiao, Zhao Ji-Hong, Cai Yu, Zhong Hao-Yan
Department of Stomatology, Gezhouba Central Hospital, Third Clinical College, Three Gorge University. Yichang 443002, China E-mail:
Shanghai Kou Qiang Yi Xue. 2016 Oct;25(5):588-592.
To compare the clinical efficacy of pingyangmycin and lauromacrogol combined with pingyangmycin in the treatment of venous malformations (VMs).
One hundred and twenty patients with VM were randomly divided into lauromacrogol combined with pingyangmycin injection group (experimental group) and pingyangmycin injection group (control group). The appropriate interval between different injection sessions was 2 weeks. After different sessions, the changes of lesions (including size, color, texture) as well as the results of posture test and adverse effects were analyzed by using SPSS11.5 software package.
According to the international evaluation criteria for VM, the efficacy of the experimental group was significantly better than the control group after 2~5 sessions (P<0.05). However, after 1 and 6 sessions, there was no significant difference in the efficacy between the experimental group and the control group (P>0.05). In addition, the average sessions required in the experimental group were significantly less than those in the control group (P<0.05).
Compared to the single use of pingyangmycin, lauromacrogol combined with pingyangmycin is more effective for the treatment of VM, with fewer sessions required and no adverse effects.
比较平阳霉素与聚桂醇联合平阳霉素治疗静脉畸形（VMs）的临床疗效。
将120例VM患者随机分为聚桂醇联合平阳霉素注射组（试验组）和平阳霉素注射组（对照组）。不同注射疗程之间的合适间隔为2周。不同疗程后，使用SPSS11.5软件包分析病变的变化（包括大小、颜色、质地）以及体位试验结果和不良反应。
根据VM的国际评估标准，试验组在2至5个疗程后的疗效明显优于对照组（P<0.05）。然而，在1个疗程和6个疗程后，试验组与对照组的疗效无显著差异（P>0.05）。此外，试验组所需的平均疗程明显少于对照组（P<0.05）。
与单用平阳霉素相比，聚桂醇联合平阳霉素治疗VM更有效，所需疗程更少且无不良反应。
