Moore Alessandra L, Marshall Clement D, Longaker Michael T
Division of General and Gastrointestinal Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA.
Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
J Funct Biomater. 2017 Jan 21;8(1):3. doi: 10.3390/jfb8010003.
Wound healing continues to be a major burden to patients, though research in the field has expanded significantly. Due to an aging population and increasing comorbid conditions, the cost of chronic wounds is expected to increase for patients and the U.S. healthcare system alike. With this knowledge, the number of engineered products to facilitate wound healing has also increased dramatically, with some already in clinical use. In this review, the major biomaterials used to facilitate skin wound healing will be examined, with particular attention allocated to the science behind their development. Experimental therapies will also be evaluated.
尽管该领域的研究有了显著扩展，但伤口愈合仍是患者的一大负担。由于人口老龄化和合并症增多，慢性伤口给患者和美国医疗系统带来的成本预计都会增加。基于这一认知，用于促进伤口愈合的工程产品数量也大幅增加，有些已经投入临床使用。在本综述中，将研究用于促进皮肤伤口愈合的主要生物材料，并特别关注其研发背后的科学原理。还将评估实验性疗法。
