Adler C H, Stern M B, Brooks M L
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia.
Mov Disord. 1989;4(4):333-7. doi: 10.1002/mds.870040407.
A 24-year-old man with an 11-year history of i.v. drug use rapidly developed parkinsonism clinically indistinguishable from MPTP toxicity and Parkinson's disease. Although tests were negative for the human immunodeficiency virus, radiologic evaluation revealed bilateral striatal lesions. Stereotactic biopsy demonstrated septate hyphae consistent with either aspergillosis or mucormycosis. Gradual improvement followed systemic therapy with amphotericin B.
一名有11年静脉注射毒品史的24岁男子迅速出现临床上与MPTP毒性及帕金森病难以区分的帕金森综合征。尽管人类免疫缺陷病毒检测呈阴性，但影像学评估显示双侧纹状体病变。立体定向活检显示有符合曲霉菌病或毛霉菌病的分隔菌丝。全身应用两性霉素B治疗后病情逐渐改善。
