Neuhäuser-Klaus A, Lehmacher W
Institut für Säugetiergenetik, Gesellschaft für Strahlen- und Umweltforschung (GSF), Neuherberg F.R.G.
Mutat Res. 1989 Nov;224(3):369-71. doi: 10.1016/0165-1218(89)90182-1.
The mouse spot test was used to investigate the in vivo mutagenicity of caprolactam. Among offspring treated with 500 mg/kg, the frequency of spots was increased over controls in 4 separate experiments, leading to the conclusion that caprolactam is mutagenic in the spot test.
采用小鼠斑点试验研究己内酰胺的体内致突变性。在4个独立实验中,用500mg/kg己内酰胺处理的子代斑点频率高于对照组,由此得出己内酰胺在斑点试验中具有致突变性的结论。