Salamone M F
Ontario Ministry of the Environment, Biohazard Laboratory, Rexdale, Canada.
Mutat Res. 1989 Nov;224(3):385-9. doi: 10.1016/0165-1218(89)90186-9.
Benzoin and caprolactam, two noncarcinogenic chemicals found in association with consumer products, were tested in the mammalian in vivo abnormal spermhead assay. Each chemical was dissolved in a pharmaceutical grade corn oil and administered by gavage. Toxic effects were observed only with caprolactam-treated mice. Neither benzoin nor caprolactam induced a significant increase in the frequency of abnormal sperm as compared to that for animals treated only with the corn oil.
安息香和己内酰胺是在消费品中发现的两种非致癌化学物质,它们在哺乳动物体内异常精子头试验中接受了测试。每种化学物质都溶解在药用级玉米油中,并通过灌胃给药。仅在己内酰胺处理的小鼠中观察到了毒性作用。与仅用玉米油处理的动物相比,安息香和己内酰胺均未引起异常精子频率的显著增加。