Postorino Valentina, Scahill Lawrence, De Peppo Lavinia, Fatta Laura Maria, Zanna Valeria, Castiglioni Maria Chiara, Gillespie Scott, Vicari Stefano, Mazzone Luigi
Department of pediatrics, The Marcus Autism Center, Emory University School of Medicine, 1920 Briarcliff Road, NE, Atlanta, GA, 30329, USA.
Child Neuropsychiatry Unit, Department of Neuroscience, I.R.C.C.S. Children's Hospital Bambino Gesù, Piazza S. Onofrio 4, 00165, Rome, Italy.
J Autism Dev Disord. 2017 Apr;47(4):1051-1061. doi: 10.1007/s10803-016-3023-y.
This study aimed to examine the presence of Autism Spectrum Disorder (ASD) in a sample of female adolescents with Anorexia Nervosa (AN) during the acute phase of illness. We also compare the level of autistic traits, social perception skills and obsessive-compulsive symptoms in four groups: AN, ASD, and two gender- and age-matched control groups. Of the 30 AN participants, only three scored above the conventional ADOS-2 threshold for ASD. The AN participants were similar to their controls on autistic trait measures, and to the ASD group on obsessive-compulsive measures, and on theory of mind ability and affect recognition measures. Further longitudinal studies are needed in order to determine the association between these conditions.
本研究旨在检测患有神经性厌食症（AN）的女性青少年急性期样本中自闭症谱系障碍（ASD）的存在情况。我们还比较了四组人群的自闭症特征水平、社会认知技能和强迫症状：神经性厌食症组、自闭症谱系障碍组，以及两个性别和年龄匹配的对照组。在30名神经性厌食症参与者中，只有三人的自闭症诊断观察量表第二版（ADOS-2）得分高于ASD的传统阈值。神经性厌食症参与者在自闭症特征测量方面与对照组相似，在强迫测量、心理理论能力和情感识别测量方面与自闭症谱系障碍组相似。为了确定这些病症之间的关联，还需要进一步的纵向研究。
