Pandian Rajadoss Muthukrishna, John Nirmal Thampi, Eapen Anu, Antonisamy B, Devasia Antony, Kekre Nitin
Department of Urology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
Department of Radiology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
Int Braz J Urol. 2017 Jan-Feb;43(1):127-133. doi: 10.1590/S1677-5538.IBJU.2016.0252.
To study the usefulness of MRI in preoperative evaluation of PFUDD. Can MRI provide additional information on urethral distraction defect (UDD) and cause of erectile dysfunction (ED)?
In this prospective study, consecutive male patients presenting with PFUDD were included from Feb 2011 till Dec 2012. Those with traumatic spinal cord injury and pre-existing ED were excluded. Patients were assessed using IIEF questionnaire, retrograde urethrogram and micturating cystourethrogram (RGU+MCU) and MRI pelvis. Primary end point was erectile function and secondary end point was surgical outcome.
Twenty patients were included in this study. Fourteen patients (70%) were ≤40years; fifteen patients (75%) had ED, seven patients (35%) had severe ED. MRI findings associated with ED were longer median UDD (23mm vs. 15mm, p=0.07), cavernosal injury (100%, p=0.53), rectal injury (100%, p=0.53), retropubic scarring (60%, p=0.62) and prostatic displacement (60%, p=0.99). Twelve patients (60%) had a good surgical outcome, five (25%) had an acceptable outcome, three (15%) had a poor outcome. Poor surgical outcome was associated with rectal injury (66.7%, p=0.08), cavernosal injury (25%, p=0.19), retropubic scarring (18.1%, p=0.99) and prostatic displacement (16.7%, p=0.99). Five patients with normal erections had good surgical outcome. Three patients with ED had poor outcome (20%, p=0.20).
MRI did not offer significant advantage over MCU in the subgroup of men with normal erections. Cavernosal injury noted on MRI strongly correlated with ED. Role of MRI may be limited to the subgroup with ED or an inconclusive MCU.
研究磁共振成像(MRI)在耻骨后尿道下裂(PFUDD)术前评估中的作用。MRI能否提供有关尿道牵张缺损(UDD)和勃起功能障碍(ED)病因的额外信息?
在这项前瞻性研究中,纳入了2011年2月至2012年12月连续就诊的患有PFUDD的男性患者。排除有创伤性脊髓损伤和既往存在ED的患者。使用国际勃起功能指数(IIEF)问卷、逆行尿道造影和排尿性膀胱尿道造影(RGU+MCU)以及盆腔MRI对患者进行评估。主要终点是勃起功能,次要终点是手术结果。
本研究共纳入20例患者。14例患者(70%)年龄≤40岁;15例患者(75%)患有ED,7例患者(35%)患有重度ED。与ED相关的MRI表现为UDD中位数较长(23mm对15mm,p=0.07)、海绵体损伤(100%,p=0.53)、直肠损伤(100%,p=0.53)、耻骨后瘢痕形成(60%,p=0.62)和前列腺移位(60%,p=0.99)。12例患者(60%)手术结果良好,5例(25%)结果尚可,3例(15%)结果较差。手术结果差与直肠损伤(66.7%,p=0.08)、海绵体损伤(25%,p=0.19)、耻骨后瘢痕形成(18.1%,p=0.99)和前列腺移位(16.7%,p=0.99)有关。5例勃起功能正常的患者手术结果良好。3例患有ED的患者结果较差(20%,p=0.20)。
在勃起功能正常的男性亚组中,MRI相对于排尿性膀胱尿道造影(MCU)没有显著优势。MRI上发现的海绵体损伤与ED密切相关。MRI的作用可能仅限于患有ED或MCU结果不明确的亚组。