Gomiero Tiziano, Bertelli Marco, Deb Shoumitro, Weger Elisabeth, Marangoni Annachiara, De Bastiani Elisa, Mantesso Ulrico, De Vreese Luc Pieter
DAD© Project Group, ANFFAS TRENTINO ONLUS, Via Unterveger, 6/A, 38121 - Trento. Italy.
Research and Clinical Centre (CREA) of San Sebastiano Foundation, Florence. Italy.
Curr Alzheimer Res. 2017;14(7):709-721. doi: 10.2174/1567205014666170117094757.
The USA National Task Group (NTG) guidelines advocate the use of an adapted version of Dementia Screening Questionnaire for Individuals with Intellectual Disabilities (DSQIID) for dementia screening of individuals with Down syndrome (DS) and with other forms of ID (non-DS).
In order to meet these guidelines, this study verifies the psychometric properties of an Italian version of the original DSQIID in a population composed of adults aged 40 years and over with DS and non-DS ID.
Internal consistency, inter-rater and intra-rater reliabilities, structural validity, convergent validity and known group differences of DSQIID-I were assessed with 200 individuals with ID (mean of 55.2 years; range: 40-80 years) recruited from 15 different centers in Italy. Diagnosis of dementia was done according to IASSID diagnostic criteria and its degree of clinical certainty was defined according to Silverman et al.'s classification (2004).
Cronbach's alpha for the DSQIID-I was 0.94. The ICCs for inter-rater and test-retest reliability were both 0.89. A Principal Component analysis revealed three domains, namely memory and confusion- related items, motor and functional disabilities, depression and apathy, which explained almost 40% of the overall variance. The total DSQIID-I score correlated significantly with DMR and differed significantly among those individuals (n = 34) with cognitive decline from those without (n = 166). Age, gender and severity of ID were unrelated to the DSQIID-I.
The present study confirms the cross-cultural value of DSQIID which was proved to be a psychometrically valid and user-friendly observer-rated scale for dementia screening in adults with both DS and non-DS ID.
美国国家任务组（NTG）指南提倡使用《智力残疾者痴呆筛查问卷》（DSQIID）的改编版，对唐氏综合征（DS）患者和其他形式智力残疾（非DS）患者进行痴呆筛查。
为符合这些指南，本研究在一个由40岁及以上患有DS和非DS智力残疾的成年人组成的群体中，验证了意大利语版原始DSQIID的心理测量特性。
从意大利15个不同中心招募了200名智力残疾者（平均年龄55.2岁；范围：40 - 80岁），评估DSQIID - I的内部一致性、评分者间和评分者内信度、结构效度、收敛效度以及已知组间差异。根据国际智力障碍科学委员会（IASSID）诊断标准进行痴呆诊断，并根据西尔弗曼等人（2004年）的分类定义其临床确定性程度。
DSQIID - I的克朗巴哈系数为0.94。评分者间信度和重测信度的组内相关系数均为0.89。主成分分析揭示了三个领域：即与记忆和困惑相关的项目、运动和功能障碍、抑郁和冷漠，它们解释了总方差的近40%。DSQIID - I总分与痴呆评定量表（DMR）显著相关，并且在认知功能下降者（n = 34）和未下降者（n = 166）之间存在显著差异。年龄、性别和智力残疾严重程度与DSQIID - I无关。
本研究证实了DSQIID的跨文化价值，该量表被证明是一种心理测量有效且用户友好的、由观察者评定量表，用于对患有DS和非DS智力残疾的成年人进行痴呆筛查。
