Department of Industrial Hygiene, Department of the Navy, Naval Hospital Bremerton, Bremerton, Washington.
Department of Safety Sciences, Indiana University of Pennsylvania, Indiana, Pennsylvania.
Am J Ind Med. 2017 Mar;60(3):227-238. doi: 10.1002/ajim.22690. Epub 2017 Jan 27.
Studies suggest metal and solvent exposure may damage hearing. This study evaluated the association between exposures classified as high for metals, solvents, and noise on permanent threshold shift (PTS) development.
A total of 1,546 personnel at an industrial shipyard were divided into five exposure groups based on level of concentration: high noise, high metals/solvents, high metals/noise, high metals/solvents/noise, and a low metals/solvents/noise reference group. Hearing threshold changes were analyzed to identify development of a PTS.
Logistic regression indicated high metals/solvents and high metals/solvent/noise groups had significantly greater odds ratios of 2.4; 95%CI [1.02, 2.85] and 1.7; 95%CI [1.46, 3.94], respectively, compared to a reference group. Both groups were associated with PTSs while controlling for age, gender, and exposure duration.
Simultaneous exposures classified as high for metals and solvents may damage hearing. Results suggest the need for expanding hearing conservation programs to consider combinations of exposures to metals, solvents, and noise. Am. J. Ind. Med. 60:227-238, 2017. © 2017 Wiley Periodicals, Inc.
研究表明金属和溶剂暴露可能会损害听力。本研究评估了分类为金属、溶剂和噪声高暴露水平对永久性阈移（PTS）发展的影响。
共有 1546 名工业造船厂的人员根据浓度水平分为五个暴露组：高强度噪声、高强度金属/溶剂、高强度金属/噪声、高强度金属/溶剂/噪声和低强度金属/溶剂/噪声参考组。分析听力阈值变化以确定 PTS 的发展。
逻辑回归表明，高强度金属/溶剂和高强度金属/溶剂/噪声组的比值比显著增加，分别为 2.4；95%CI [1.02, 2.85]和 1.7；95%CI [1.46, 3.94]，与参考组相比。在控制年龄、性别和暴露持续时间的情况下，两组均与 PTS 相关。
同时暴露于高浓度的金属和溶剂可能会损害听力。结果表明，有必要扩大听力保护计划，以考虑金属、溶剂和噪声的组合暴露。美国工业医学杂志 60:227-238, 2017. © 2017 威利父子公司。
