Mohammad Kaveh, Thomson Douglas J
IEEE Trans Biomed Circuits Syst. 2017 Apr;11(2):392-399. doi: 10.1109/TBCAS.2016.2616346. Epub 2017 Jan 23.
A simple high frequency capacitance sensor with 180 aF sensitivity is designed for a wide range of microfluidic applications. The sensor is implemented utilizing differential ring oscillators operating at [Formula: see text] MHz with a differential signal at [Formula: see text] MHz. The sensor occupies [Formula: see text] cm × 2 cm on a printed circuit board. The sensor is tuned using two precision variable capacitors and has a full scale range of [Formula: see text] pF. The sensor was able to detect less than 1% Isopropyl Alcohol in DI water and to detect 15 μm polystyrene spheres flowing over 25 μm lines and spaces coplanar electrodes in a microfluidic channel. The compact differential ring oscillator based architecture of the design makes it suitable to be integrated into microprocessor based systems for detection in Lab on Chip or Lab on Board applications.
一款灵敏度为180阿法的简单高频电容传感器专为广泛的微流体应用而设计。该传感器利用工作在[公式：见正文]兆赫兹的差分环形振荡器实现，具有[公式：见正文]兆赫兹的差分信号。该传感器在印刷电路板上占据[公式：见正文]厘米×2厘米的面积。该传感器使用两个精密可变电容器进行调谐，满量程范围为[公式：见正文]皮法。该传感器能够检测去离子水中浓度低于1%的异丙醇，还能检测在微流体通道中25微米线和间隔的共面电极上流动的15微米聚苯乙烯球体。该设计基于紧凑的差分环形振荡器架构，使其适合集成到基于微处理器的系统中，用于芯片实验室或板载实验室应用中的检测。
