Henriquez A, Latorre J J, Gonzalez S
Department of Pediatric Pathology, Hospital Luis Calvo Mackenna, Santiago de Chile.
Pediatr Pathol. 1989;9(5):559-66. doi: 10.3109/15513818909026914.
A myxoid mesocolic tumor in a 4-month-old female infant is described. The tumor weighed 190 g and measured 8 cm in diameter and presented as a single mass composed of stellate and round cells with vesicular nuclei and prominent nucleoli in a myxoid, well-vascularized stroma. Electron microscopy showed mesenchymal cells with dilated rough endoplasmic reticulum, cell projections with primitive and desmosome-like cell junctions, and basal membrane-like material. Immunohistochemical studies demonstrated immunoreactivity with antibodies against vimentin and S-100 protein. The infant is well and without evidence of disease 3 years after surgery. This is an example of a peripheral myxoid hamartoma with neural differentiation, and the tumor is expected to have a benign clinical course.
本文描述了一名4个月大女婴的黏液样结肠系膜肿瘤。该肿瘤重190克，直径8厘米，表现为单个肿块，由星状和圆形细胞组成，细胞核呈泡状，核仁明显，位于黏液样、血管丰富的间质中。电子显微镜显示间充质细胞的粗面内质网扩张，细胞突起有原始的和桥粒样细胞连接，以及基底膜样物质。免疫组织化学研究表明，该肿瘤对波形蛋白和S-100蛋白抗体呈免疫反应性。术后3年，该婴儿情况良好，无疾病迹象。这是一例具有神经分化的外周黏液样错构瘤，预计该肿瘤临床病程为良性。
