[一例通过细胞学诊断的老年女性乳腺纯鳞状细胞癌病例]

[A Case of Pure Squamous Cell Carcinoma of the Breast in an Elderly Woman Diagnosed by Cytology].

作者信息

Sato Yasufumi, Inatome Junichi, Okishiro Masatsugu, Oneda Yasuo, Ishida Tomo, Morimoto Yoshihiro, Kuwahara Ryuichi, Kusama Hiroki, Naito Atsushi, Murakami Kohei, Katsura Yoshiteru, Ohmura Yoshiaki, Kagawa Yoshinori, Takeno Atsushi, Egawa Chiyomi, Takeda Yutaka, Kato Takeshi, Tamura Shigeyuki, Takatsuka Yuichi, Goto Takayoshi, Nagano Teruaki, Nakatsuka Shinichi

机构信息

Dept. of Surgery, Kansai Rosai Hospital.

出版信息

Gan To Kagaku Ryoho. 2016 Nov;43(12):2259-2261.

PMID:28133288

Abstract

A n 85-year-old woman presented with a mass in the left breast. A3 7mm lobulated mass including enhancement of a cyst of 37mm was detected by sonography. An axillary lymph node had increased to 16 mm. Atypical cells dyed by light green and orange G were identified by fine needle aspiration and cytology. She was diagnosed with left breast cancer(cT2N1M0, Stage II B), histologically suspected to be squamous cell carcinoma. She underwent a left-breast-conserving surgery and axillary lymph node dissection. On pathology, a cyst of 34×30mm was noted. The tumor grew from inside the cyst to the surround- ing tissue and it had a trend for keratinocytes. Lymph node metastases affected 1/11. By immunostaining, the tumor was found to be ER(+), PgR(-), HER2(-), CK5/6(+), p40(+), mammaglobin(-), and GCDFP15(-). There was no component of ductal carcinoma. She received radiotherapy to the left breast and tamoxifen as an adjuvant therapy. Squamous cell carcinoma of the breast is rare. We encountered a case of pure squamous cell carcinoma of the breast in an elderly woman. We report this case with a discussion of the relevant literature.

摘要

一名85岁女性因左乳肿物就诊。超声检查发现一个37mm的分叶状肿物，其中包括一个37mm囊肿的强化。一个腋窝淋巴结增大至16mm。通过细针穿刺和细胞学检查发现了被淡绿色和橘黄G染色的非典型细胞。她被诊断为左乳腺癌（cT2N1M0，IIB期），组织学上怀疑为鳞状细胞癌。她接受了保乳手术和腋窝淋巴结清扫术。病理检查发现一个34×30mm的囊肿。肿瘤从囊肿内部生长至周围组织，有角质形成细胞的趋势。淋巴结转移为1/11。通过免疫染色，发现肿瘤为ER(+)、PgR(-)、HER2(-)、CK5/6(+)、p40(+)、乳腺珠蛋白(-)和GCDFP15(-)。没有导管癌成分。她接受了左乳放疗和他莫昔芬辅助治疗。乳腺鳞状细胞癌很罕见。我们遇到了一例老年女性单纯乳腺鳞状细胞癌的病例。我们报告该病例并讨论相关文献。