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[来自荨麻水提取物的生物活性化合物]

[Biologically active compounds from the aqueous extract of Urtica dioica].

作者信息

Wagner H, Willer F, Kreher B

出版信息

Planta Med. 1989 Oct;55(5):452-4. doi: 10.1055/s-2006-962062.

DOI:10.1055/s-2006-962062
PMID:2813580
Abstract

From the water extract of the roots of Urtica dioica (stinging nettle) a polysaccharide fraction was isolated which revealed activity in the carrageenan rat paw edema model and lymphocyte transformation test. Ion exchange chromatography and gel filtration of this fraction afforded 4 different polysaccharides, one of which reduced dose dependent hemolysis in the classical pathway of the complement test. The Urtica dioica lectin (UDA) was reisolated and found to stimulate the proliferation of human lymphocytes.

摘要

从荨麻(Urtica dioica)根的水提取物中分离出一种多糖组分,该组分在角叉菜胶诱导的大鼠足肿胀模型和淋巴细胞转化试验中显示出活性。对该组分进行离子交换色谱和凝胶过滤得到4种不同的多糖,其中一种在补体经典途径试验中能剂量依赖性地减少溶血。重新分离出荨麻凝集素(UDA),发现其能刺激人淋巴细胞的增殖。

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