Fukunishi I, Hayabara T, Morioka E, Izumi H, Hosokawa K
Seishin Shinkeigaku Zasshi. 1989;91(6):401-28.
Epidemiological investigation of senile dementia was performed in 1987 and 1988 on all the aged at home (3,754 persons at the ages of 65 years or more) in Miki-cho (M-cho), Kagawa Prefecture. The composition of the population in M-cho is similar to that in Kagawa Prefecture. M-cho has the most population among the towns or villages in Kagawa Prefecture. Urban areas, rural areas, and middle areas are distributed evenly in respect to the size in M-cho. Thus, it was possible to carry out the investigation reflecting the situation in Kagawa Prefecture. The results of the present investigation were as follows. 1) The prevalence rate was 4.1% in both the first year (1987) and the second year (1988). 2) The incidence rate was 1.01%. 3) The proportion of Alzheimer type dementia to cerebrovascular type dementia was 0.98 in the first year and 1.00 in the second year. 4) Although no statistically significant difference in the prevalence rate was noted between males and females, the prevalence rate of males was higher than that of females in the first half of senility, and the prevalence rate of females was higher than that of males in the second half of senility. 5) Although no statistically significant difference in the prevalence rate was noted between Alzheimer type dementia and cerebrovascular type dementia, the prevalence rate of cerebrovascular type was higher than that of Alzheimer type in the first half of senility, and the prevalence rate of Alzheimer type was higher than that of cerebrovascular type in the second half of senility. The epidemiological investigations of senile dementia have been often reported in all over the world. However, most of the investigations were made on nothing but the calculation of the prevalence rate of senile dementia, while the investigation of the incidence rate was hardly carried out. In respect to the incidence rate, it is desirable that the subjects should be more than 1,000 in number. When the number of subjects is less than 1,000, the occurrence of senile dementia will be noted yearly in approximately 10 cases. If the number of patients with senile dementia increases or decreases even by one, therefore, the incidence rate differs to a great extent. The past reports on the incidence rate were made in subjects of less than 1,000 in number. Accordingly, it may be possible to say that the present investigation was made by the exact methods accompanied by less errors.(ABSTRACT TRUNCATED AT 400 WORDS)
1987年和1988年,对香川县三木町(M町)所有65岁及以上的老年人(共3754人)进行了老年痴呆症的流行病学调查。M町的人口构成与香川县相似。M町是香川县内町村人口最多的地区。M町的城市、农村和中部地区在规模上分布均匀。因此,有可能开展反映香川县情况的调查。本次调查结果如下:1)第一年(1987年)和第二年(1988年)的患病率均为4.1%。2)发病率为1.01%。3)阿尔茨海默型痴呆与脑血管型痴呆的比例在第一年为0.98,第二年为1.00。4)虽然男性和女性的患病率在统计学上没有显著差异,但在老年前期男性患病率高于女性,在老年后期女性患病率高于男性。5)虽然阿尔茨海默型痴呆和脑血管型痴呆的患病率在统计学上没有显著差异,但在老年前期脑血管型患病率高于阿尔茨海默型,在老年后期阿尔茨海默型患病率高于脑血管型。世界各地经常报道老年痴呆症的流行病学调查。然而,大多数调查仅仅是计算老年痴呆症的患病率,而发病率的调查几乎没有进行。关于发病率,理想的情况是研究对象应超过1000人。当研究对象数量少于1000人时,每年大约会有10例老年痴呆症病例出现。因此,如果老年痴呆症患者数量增加或减少哪怕一人,发病率都会有很大差异。过去关于发病率的报告所涉及的研究对象数量都少于1000人。因此,可以说本次调查采用了误差较小的精确方法。(摘要截选至400字)