Rajshekhar Vedantam
Department of Neurological Sciences, Christian Medical College & Hospital, Vellore, India.
Indian J Med Res. 2016 Sep;144(3):319-326. doi: 10.4103/0971-5916.198686.
Neurocysticercosis (NCC) is the most common single cause of seizures/epilepsy in India and several other endemic countries throughout the world. It is also the most common parasitic disease of the brain caused by the cestode Taenia solium or pork tapeworm. The diagnosis of NCC and the tapeworm carrier (taeniasis) can be relatively inaccessible and expensive for most of the patients. In spite of the introduction of several new immunological tests, neuroimaging remains the main diagnostic test for NCC. The treatment of NCC is also mired in controversy although, there is emerging evidence that albendazole (a cysticidal drug) may be beneficial for patients by reducing the number of seizures and hastening the resolution of live cysts. Currently, there are several diagnostic and management issues which remain unresolved. This review will highlight some of these issues.
神经囊尾蚴病(NCC)是印度以及世界上其他几个流行国家癫痫发作/癫痫最常见的单一病因。它也是由绦虫猪带绦虫引起的最常见的脑部寄生虫病。对于大多数患者而言,NCC和绦虫携带者(猪带绦虫病)的诊断可能相对难以实现且费用高昂。尽管引入了多种新的免疫检测方法,但神经影像学检查仍然是NCC的主要诊断手段。NCC的治疗也存在争议,不过,越来越多的证据表明阿苯达唑(一种杀囊药物)可能对患者有益,可减少癫痫发作次数并加速活囊的消退。目前,仍有几个诊断和管理问题尚未解决。本综述将重点介绍其中的一些问题。