Elashoff R M, Lee J J, Afifi A A
Department of Biostatistics (School of Public Health), University of California, Los Angeles 90024.
Stat Med. 1989 Oct;8(10):1269-76. doi: 10.1002/sim.4780081010.
Two new methods are proposed for constructing the confidence limits for quartiles. The small sample behaviour of these two methods is compared with the Jennison and Turnbull modified Brookmeyer-Crowley method at three quartiles. The simulation study indicates that one of the new methods, the smoothed modified reflected method, is preferred over the other methods when the censoring rate is less than 40 per cent while the Jennison and Turnbull method is preferred for higher censoring. The results for the upper quartile are similar to the median. For the lower quartile with small sample and high censoring, semi-infinite intervals may often occur. The correct practice is to permit the semi-infinite intervals without modifying them since it is more informative and gives closer to nominal level coverage.
提出了两种构建四分位数置信区间的新方法。将这两种方法在三个四分位数处的小样本行为与詹尼森和特恩布尔改进的布鲁克迈尔-克劳利方法进行了比较。模拟研究表明,当删失率小于40%时,新方法之一,即平滑修正反射法,优于其他方法,而对于较高的删失率,詹尼森和特恩布尔方法更受青睐。上四分位数的结果与中位数相似。对于小样本和高删失率的下四分位数,半无限区间经常会出现。正确的做法是允许半无限区间而不进行修改,因为这样更具信息性,并且能提供更接近名义水平的覆盖率。