Calvo Felipe A
Department of Radiation Oncology, Department of Oncology, Hospital general Universitario Gregorio Marañon, Complutense University of Madrid, Madrid, Spain.
Instituto de Investigación Sanitaria Gregorio Marañon, Grupo Oncologia Interdisciplinar y Biotecnológica. Proyecto PI15/02121, Madrid, Spain.
Radiat Oncol. 2017 Feb 2;12(1):36. doi: 10.1186/s13014-017-0764-5.
Intraoperative irradiation was implemented 4 decades ago, pioneering the efforts to improve precision in local cancer therapy by combining real-time surgical exploration/resection with high single dose radiotherapy (Gunderson et al., Intraoperative irradiation: techniques and results, 2011). Clinical and technical developments have led to very precise radiation dose deposit. The ability to deliver a very precise dose of radiation is an essential element of contemporary multidisciplinary individualized oncology.This issue of Radiation Oncology contains a collection of expert review articles and updates with relevant data regarding intraoperative radiotherapy. Technology, physics, biology of single dose and clinical results in a variety of cancer sites and histologies are described and analyzed. The state of the art for advanced cancer care through medical innovation opens a significant opportunity for individualize cancer management across a broad spectrum of clinical practice. The advantage for tailoring diagnostic and treatment decisions in an individualized fashion will translate into precise medical treatment.
术中放疗始于40年前，通过将实时手术探查/切除与高单次剂量放疗相结合，开创了提高局部癌症治疗精准度的先河（冈德森等人，《术中放疗：技术与结果》，2011年）。临床和技术的发展已实现了非常精确的放射剂量沉积。能够提供非常精确的放射剂量是当代多学科个体化肿瘤学的一个基本要素。本期《放射肿瘤学》刊载了一系列专家综述文章以及有关术中放疗的相关数据更新。文章描述并分析了单剂量放疗的技术、物理学、生物学以及在各种癌症部位和组织学类型中的临床结果。通过医学创新实现先进癌症护理的最新技术为广泛临床实践中的个体化癌症管理带来了重大机遇。以个体化方式定制诊断和治疗决策的优势将转化为精确的医学治疗。
