Southern Illinois University-Edwardsville School of Pharmacy, United States.
University of Wisconsin-Madison School of Pharmacy, United States.
Res Social Adm Pharm. 2018 Jan;14(1):46-52. doi: 10.1016/j.sapharm.2016.12.011. Epub 2017 Jan 23.
Asthma is an expensive chronic lung disease that affects 7% of U.S. adults and results in as many as 1.8 million emergency department (ED) visits each year. Pharmacists play an important role in managing asthma, including assessing control and monitoring disease progression, educating the patient about the disease and associated treatments, and ensuring safe and cost-effective medication use. However, comprehensive studies that account for the complex relationships between factors impacting asthma-related ED visits are lacking in the adult asthma population.
To explore the complex relationships between asthma control, medication use, co-morbid conditions, minority status, environment and asthma-related ED visits using a path analysis approach.
Data for this study were obtained from the 2012 Behavioral Risk Factor Surveillance System's Asthma Call Back Survey. Current asthmatics 18 and older were included in the sample. Path analysis was used to evaluate the direct effects of the independent variables on asthma-related ED visits, as well as the indirect effects mediated through asthma control, health status, and daily use of inhaled corticosteroids.
Having controlled asthma (β = -0.153, p < 0.01) and good health status (β = -0.133, p < 0.01) were associated with significantly fewer ED visits. Good health status was associated with daily use of inhaled corticosteroids, which in turn was associated with better asthma control. Hispanic ED use was mediated by asthma control (β = -0.067, p < 0.05), while African American ED use was mediated by health status (β = 0.050, p < 0.05).
These findings suggest that there may be race/ethnicity specific factors that may be targeted to reduce asthma-related ED visits in minority populations.
哮喘是一种昂贵的慢性肺部疾病,影响美国 7%的成年人,每年导致多达 180 万人次前往急诊部(ED)就诊。药剂师在管理哮喘方面发挥着重要作用,包括评估控制情况和监测疾病进展、向患者教育疾病和相关治疗方法、确保安全和具有成本效益的药物使用。然而,在成年哮喘人群中,缺乏全面考虑影响哮喘相关 ED 就诊的复杂因素的研究。
采用路径分析方法探讨哮喘控制、药物使用、合并症、少数民族地位、环境与哮喘相关 ED 就诊之间的复杂关系。
本研究的数据来自 2012 年行为风险因素监测系统哮喘回拨调查。将 18 岁及以上的现患哮喘者纳入样本。采用路径分析评估独立变量对哮喘相关 ED 就诊的直接影响,以及通过哮喘控制、健康状况和每日使用吸入性皮质类固醇间接影响。
控制良好的哮喘(β=-0.153,p<0.01)和良好的健康状况(β=-0.133,p<0.01)与 ED 就诊次数显著减少相关。良好的健康状况与每日使用吸入性皮质类固醇相关,而吸入性皮质类固醇又与更好的哮喘控制相关。西班牙裔 ED 使用通过哮喘控制(β=-0.067,p<0.05)进行中介,而非裔美国人 ED 使用通过健康状况(β=0.050,p<0.05)进行中介。
这些发现表明,可能存在针对特定种族/民族的因素,以减少少数民族群体中与哮喘相关的 ED 就诊。