Department of Biobehavioral Health and Population Science, University of Minnesota Medical School, Duluth, MN 55812, USA.
Eur Addict Res. 2013;19(1):1-6. doi: 10.1159/000338285. Epub 2012 Aug 28.
To date there are very few laboratory data available regarding the long-term effect of the psychostimulant khat on human neurocognitive functioning. The purpose of the present study was to assess whether chronic khat users would demonstrate impairments in working memory and speed of information processing compared to control subjects. Working memory was assessed using the forward and backward digit span test. Speed of information processing was assessed using the Digit Symbol Substitution Test. Results of the present study indicate that chronic khat use may have a long-term deleterious effect on working memory, particularly on digit backwards measures of short-term/working memory. The finding is consistent with results seen by several investigators in samples of methamphetamine users.
迄今为止,关于兴奋剂阿拉伯茶对人类神经认知功能的长期影响,实验室数据非常有限。本研究的目的是评估慢性阿拉伯茶使用者是否在工作记忆和信息处理速度方面与对照组相比存在损害。工作记忆使用顺背和倒背数字广度测试进行评估。信息处理速度使用数字符号替代测试进行评估。本研究的结果表明,慢性阿拉伯茶使用可能对工作记忆产生长期的有害影响,特别是对短期/工作记忆的数字倒背测试。这一发现与几位研究人员在甲基苯丙胺使用者样本中观察到的结果一致。