Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Magn Reson Med. 2017 Dec;78(6):2203-2215. doi: 10.1002/mrm.26620. Epub 2017 Feb 2.
The purpose of this work is to derive and demonstrate constrained-phase dual-echo Dixon imaging within a maximum likelihood framework solved with a regularized graph-cuts-guided optimization.
Dual-echo Dixon reconstruction is fundamentally underdetermined; however, adopting a constrained-phase signal model reduces the number of unknowns and the nonlinear problem can be solved under a maximum likelihood framework. Period shifts in the field map (manifesting as fat/water signal swaps) must also be corrected. Here, a regularized cost function promotes a smooth field map and is solved with a graph-cuts-guided greedy binary optimization. The reconstruction shown here is compared to two other prevalent Dixon reconstructions in experimental phantom and human studies.
Reconstructed images of the water and fat signal are shown for a phantom study, and in vivo studies of foot/ankle, pelvis, and CE-MRA of the thighs. The method shown here compared favorably with the other two methods. Large field inhomogeneities on the order of 20 ppm were resolved, thereby avoiding the fat and water signal swaps present in images reconstructed with the other methods.
Constrained-phase dual-echo Dixon imaging solved with a regularized graph-cuts-guided optimization has been derived and demonstrated to successfully separate water and fat images in the presence of large magnetic field inhomogeneities. Magn Reson Med 78:2203-2215, 2017. © 2017 International Society for Magnetic Resonance in Medicine.
本研究旨在推导并展示一种基于正则化图割引导优化的最大似然框架下的约束相位双回波 Dixon 成像方法。
双回波 Dixon 重建从根本上说是欠定的;然而,采用约束相位信号模型可以减少未知数的数量,并可以在最大似然框架下解决非线性问题。磁场图中的周期移动(表现为脂肪/水信号交换)也必须进行校正。在这里,正则化代价函数促进了磁场图的平滑,并通过图割引导的贪婪二进制优化来求解。本文展示的重建方法与实验体模和人体研究中的另外两种流行的 Dixon 重建方法进行了比较。
对体模研究中的水和脂肪信号进行了重建图像显示,以及对足部/踝关节、骨盆和大腿 CE-MRA 的活体研究。与另外两种方法相比,本文展示的方法表现更好。解决了 20ppm 量级的大磁场不均匀性,从而避免了使用其他方法重建图像时出现的脂肪和水信号交换。
基于正则化图割引导优化的约束相位双回波 Dixon 成像已被推导并证明可成功地在存在大磁场不均匀性的情况下分离水和脂肪图像。磁共振医学 78:2203-2215, 2017。© 2017 国际磁共振学会。